Serum Pharmacokinetics of a Highly Concentrated Buprenorphine Formulation in Older Female Sprague-Dawley Rats (Rattus norvegicus). [PDF]
Galang KG, Knych HK, Oates RS.
europepmc +1 more source
Perturbation‐induced responses improved seizure forecasting in epileptic rats
Abstract Objective The unpredictability of seizures is one of the most challenging aspects of uncontrolled epilepsy for patients. Prior work forecasting seizure risk has measured changes in passive intracranial electroencephalographic (EEG) signals, but currently, there are no such clinical devices available.
Wei‐Chih Chang +6 more
wiley +1 more source
A comparative study of the effects of three modes of 4-Nitroquinoline N-oxide induction of Sprague Dawley rats in animal models of oral leukoplakia. [PDF]
Jiao M +8 more
europepmc +1 more source
Non-Targeted Analysis (NTA) of Plasma and Liver from Sprague Dawley Rats Exposed to Perfluorohexanesulfonamide (PFHxSA), a Precursor to Perfluorohexane Sulfonic Acid (PFHxS) [PDF]
Denise K. MacMillan +7 more
openalex +1 more source
An algorithm for seizure detection in rodents
Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky +9 more
wiley +1 more source
Sub-chronic exposure to crude acetylene results in the development of deleterious cardio metabolic changes in Sprague Dawley rats. [PDF]
Gitonga CG +4 more
europepmc +1 more source
Absence seizures: Update on signaling mechanisms and networks
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley +1 more source
Olanzapine-induced metabolic syndrome is partially mediated by oxytocinergic system dysfunction in female Sprague-Dawley rats. [PDF]
Oduor ED +4 more
europepmc +1 more source

