Results 271 to 280 of about 441,888 (380)

Modulating Macrophage–Nucleus Pulposus Cell Crosstalk via Sequential Drug Delivery Attenuates Disc Degeneration

Advanced Science, EarlyView.
The G‐CS/MSN drug delivery system enhances intervertebral disc repair through sequential drug release. Abstract Intervertebral disc degeneration (IDD) is characterized by an inflammatory environment and dysregulation of the extracellular matrix metabolism (ECM).
Xiangzhen Kong, Rui Hu, Peng Zhang, Qi Li, Kangle Song, Hanwen Gu, Jihui Zheng, Shen Liu, Liang Liu, Lin Jin, Lei Cheng, Chengwei Li, Zhijian Wei   +12 more
wiley   +1 more source

Evaluation of Acute and Sub-Chronic Toxicity of Lactobacillus rhamnosus GG in Sprague-Dawley Rats. [PDF]

Adv Biomed Res
Vaishnavi VVK, Banik U, Sabesan GS, Adhikary AK, Parasuraman S.   +4 more
europepmc   +1 more source

DNA adduct formation and mutant induction in Sprague-Dawley rats treated with tamoxifen and its derivatives [PDF]

, 2001
Gonçalo Gamboa da Costa
openalex   +1 more source

Astrocytic ET‐1 System Determines Microglia Phenotype Following Spinal Cord Injury

Advanced Science, EarlyView.
The study reveals that astrocytic ET‐1 system is solely activated by thrombin following SCI via RhoA/NF‐κB and MAPKs/NF‐κB signal pathway. The release of astrocytic ET‐1 drives microglia polarization toward M1 phenotype through YAP signaling via ETA and ETB receptors.
Bingqiang He, Si Xu, Mengdi Li, Hui Li, Shaolan Li, Li Niu, Honghua Song, Rixin Cai, Yue Zhou, Zhilong Cao, Yingjie Wang, Yongjun Wang   +11 more
wiley   +1 more source

Investigation of urinary miRNA profile changes in amphotericin B-induced nephrotoxicity in C57BL/6 mouse, Sprague-Dawley rats and Beagle dogs. [PDF]

Toxicol Sci
Adedeji AO, Tackett MR, Tejada G, McDuffie JE.   +3 more
europepmc   +1 more source

A new species of oral Streptococcus isolated from Sprague-Dawley rats, Streptococcus orisratti sp. nov.

, 2000
Huan Zhu, Mark Willcox, K. W. Knox
openalex   +1 more source

Chronic, Severe Hypertension Does Not Impair Spatial Learning and Memory in Sprague-Dawley Rats [PDF]

, 2001
Inga Kadish, Thomas van Groen, J. Michael Wyss   +2 more
openalex   +1 more source

ALKBH5‐Mediated M6A Demethylation of G3BP1 Attenuates Ferroptosis Via Cytoplasmic Retention of YBX1/p53 in Diabetic Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
ALKBH5 promoted G3BP1 expression via m⁶A methylation at sites 142/173. G3BP1 interacts with YBX1 and p53, reducing their nuclear translocation and decreasing p53‐mediated SLC7A11 repression. This inhibites cardiomyocyte ferroptosis and mitigates myocardial damage during diabetic ischemia‐reperfusion injury.
Wenyuan Li, Wei Li, Yan Leng, Heng Xu, Zhongyuan Xia, Yao Wang   +5 more
wiley   +1 more source

Maximum Likelihood Estimation of the Prevalence of nonlethal Neoplasms [PDF]

, 1982
Chameaud, J., Chmelevsky, D., Kellerer, Albrecht M., Lafuma, J.   +3 more
core   +1 more source

Etomidate-Induced myoclonus in Sprague‒Dawley rats involves the activation of neocortical Calpain-2 and its decrement on KCC2 protein. [PDF]

BMC Anesthesiol
Feng Y, Cheng YX, Wang XH.
europepmc   +1 more source