Results 271 to 280 of about 332,610 (361)

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Expression Patterns of Cav1.3 in the Developing Stria Vascularis of Sprague-Dawley Rats. [PDF]

J Int Adv Otol
Du Z, Liu H, Chu H, Chen J.
europepmc   +1 more source

Acute intravenous exposure to silver nanoparticles during pregnancy induces particle size and vehicle dependent changes in vascular tissue contractility in Sprague Dawley rats

, 2017
Achini K. Vidanapathirana, L. C. Thompson, Maja Herco, Jillian T. Odom, Susan Sumner, Timothy R. Fennell, Jared M. Brown, Christopher J. Wingard   +7 more
openalex   +2 more sources

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

Epilepsia Open, EarlyView.
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson, Lucie Suchomelova, Claude G. Wasterlain   +2 more
wiley   +1 more source

Safety Assessment of the Ethanolic Seed Extract of <i>Mucuna pruriens</i> var. <i>pruriens</i>: Acute and Chronic Oral Toxicity Studies in Sprague-Dawley Rats. [PDF]

Pharmaceuticals (Basel)
Intatham S, Jaijoy K, Chansakaow S, Sireeratawong S.   +3 more
europepmc   +1 more source

Chemopreventive effect of diclofenac on mammary carcinogenesis in Sprague-Dawley rats

, 2013
Peter Orendáš, I Ahlers, Bianka Bojková, Monika Kassayová, Peter Kubatka, Karol Kajo, Martin Péč, E Ahlersová, L. Friedmanová   +8 more
openalex   +2 more sources

Desulfovibrio‐Hydrogen Sulfide Mediates Capsaicin‐Induced Oxidative Stress and Gut Inflammation via TXNIP/NLRP3 Pathway

Food Bioengineering, EarlyView.
ABSTRACT The intake of capsaicin can disrupt the gut microecology and impact health, yet its underlying mechanism is not fully elucidated. This study, by establishing capsaicin‐induced human microbiota‐associated (HMA) mouse models revealed the molecular mechanism by which capsaicin perturbs the gut microbiota and metabolites, leading to intestinal ...
Liangliang Zhu, Xiangru Feng, Xiaoxuan Lu, Geng Han, Jiaqi Zou, Zhaoyang Dong, Ting Luo, Jiayang Jin, Mengyao Zhao, Xiaoguo Ji, Liming Zhao   +10 more
wiley   +1 more source

The Approximate Subcutaneous LD₅₀ and Associated Lesions Induced by Ivalin, Extracted and Purified from <i>Geigeria aspera</i> Harv., in Sprague-Dawley Rats. [PDF]

Molecules
Locke S, Botha C, Clift S, Lensink A.
europepmc   +1 more source

Comparison of female Fischer and Sprague–Dawley rats in the response to ketanserin

, 2013
Chandra Suma Johnson Miryala, Cindy Hiegel, Lynda Uphouse   +2 more
openalex   +2 more sources

Infused Tiger Nut and Almond Nut Crunchy Snacks Enhanced the Nutritional Value and Antioxidant Activity in High‐Fat Diet Fed Rat

Food Chemistry International, EarlyView.
Crunches were produced from formulations of almond nuts and tiger nuts (AN–TN) for the plausible management of commodity disease of obese condition. The produced AN–TN crunches showed high consumers acceptability, phenolic, and amylopectin contents. In addition, formulated percentages of AN–TN crunches when fed to high‐fat diet (HFD) fed rats led to ...
Olufunke Florence Ajeigbe, Ayokunle Olubode Ademosun, Ganiyu Oboh, Oluwatobi Emmauel Allen, Bolaji Lawrence Awe   +4 more
wiley   +1 more source