Results 81 to 90 of about 317,880 (361)

Developmental toxic effects of ethylbenzene or toluene alone and in combination with butyl acetate in rats after inhalation exposure [PDF]

open access: yes, 2007
First, the developmental toxic potential of n-butyl acetate (BA) was examined in Sprague-Dawley rats following whole body inhalation exposure, 6 h day-1, from day 6 to 20 of gestation, at concentrations of 0, 500, 1000, 2000 and 3000 ppm.
Bourges-Abella, Nathalie   +4 more
core  

Development of Substrate‐Independent Antifouling and Bactericidal Surfaces Using Visible Light Cross‐Linked Hydrogel Coatings for Biomedical Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
A new antifouling, antithrombogenic, and bactericidal hydrogel coating method is developed for implantable medical devices. The hydrogel coating can be easily formed by visible‐light crosslinking and is universally applicable to all substrates, ranging from polymers to metals.
Soonjong Roh   +4 more
wiley   +1 more source

Biometric Data Comparison Between Lewis and Sprague Dawley Rats

open access: yesFrontiers in Veterinary Science, 2019
Introduction: Pressure mapping systems are often used for indirect assessment of kinematic gait parameter differences after repair of critical peripheral nerve defects in small animal models.
Richard Steiner   +6 more
doaj   +1 more source

CYP3A Mediated Ketamine Metabolism is Severely Impaired in Liver S9 Fractions from Aging Sprague Dawley Rats [PDF]

open access: yesarXiv, 2015
Ketamine is widely used in veterinary medicine and in medicine. Ketamine is metabolized to its active metabolite norketamine principally by liver CYP3A. Drug metabolism alterations during aging have severe consequences particularly in anesthesiology and very few studies on older animals were conducted for ketamine. The objective of the present study is
arxiv  

Controlled Release of Human Dental Pulp Stem Cell‐Derived Exosomes from Hydrogels Attenuates Temporomandibular Joint Osteoarthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia   +7 more
wiley   +1 more source

Explanation for Cancer in Rats, Mice and Humans due to Cell Phone Radiofrequency Radiation [PDF]

open access: yesarXiv, 2016
Very recently, the National Toxicology Program reported a correlation between exposure to whole body 900 MHz radiofrequency radiation and cancer in the brains and hearts of Sprague Dawley male rats. This paper proposes the following explanation for these results.
arxiv  

Two Games on Arithmetic Functions: SALIQUANT and NONTOTIENT [PDF]

open access: yesarXiv, 2023
We investigate the Sprague-Grundy sequences for two normal-play impartial games based on arithmetic functions, first described by Iannucci and Larsson in \cite{sum}. In each game, the set of positions is N (natural numbers). In saliquant, the options are to subtract a non-divisor.
arxiv  

Spontaneous Nephroblastoma in 3 Sprague-Dawley Rats

open access: yesThe Japanese Journal of Veterinary Science, 1982
SD系ラット3例に自然発生した腎臓腫瘍の病理組織学的検索を行った. 腫瘍は管を形成する一層の上皮性細胞と, その周囲に塊状に増殖する未分化な芽種性細胞から成り, 主に膠原線維から成る間質で分画されていた. この組織構築から腫瘍は腎芽腫と判断された. また, これらの上皮性細胞と芽種性細胞には電顕的に本質的な差を認めず, 組織構築が後腎胚種質に類似することと合わせ, 本腫瘍は腎実質上皮性の腫瘍であると考えられた.
Azusa Okaniwa   +4 more
openaire   +4 more sources

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray   +2 more
wiley   +1 more source

Delivery of Islatravir via High Drug‐Load, Long‐acting Microarray Patches for the Prevention or Treatment of Human Immunodeficiency Virus

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Islatravir‐loaded dissolving microarray patches (MAPs) provide a minimally invasive, long‐acting solution for HIV‐1 prevention and treatment. In rats, sustained islatravir delivery lasts up to three months, while in minipigs, efficacious plasma levels are detected for six days.
Qonita Kurnia Anjani   +11 more
wiley   +1 more source

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