Results 121 to 130 of about 745,809 (314)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Back from Beyond the Bid-Ask Spread: Estimating Liquidity in International Markets [PDF]
Research on the topic of liquidity has greatly benefited from the improved availability of data. Researchers have addressed questions regarding the factors that influence bid-ask spreads and the relationship between spreads and risk, return and liquidity.
Charles Ward, Gianluca Marcato
core
Fate of Urban Groundwater in Shallow Confined Aquifers. Case Study of Baldia Town, Karachi, Pakistan
, 2019 A study was carried out to assess the groundwater quality for drinking purpose in Baldia Town, Karachi. For this purpose, groundwater samples (n = 18) were randomly collected from various depths (> 100 feet) through boring wells after monsoon season ...
Naz, Bisma, Khan, Adnan
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Spreading of hand hygiene change package across an acute hospital
BMJ Open QualityBackground A set of interventions in a hand hygiene change package was developed in a pilot ward by the end of 2017. In 2018, Changi General Hospital embarked on scaling up the change package to other wards with the intention to eventually spread the ...
Vijo Poulose +7 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
A nearest neighbour approach to the simulation of spread of barley yellow dwarf virus
, 2000 The spread of insect vectored plant virus diseases such as barley yellow dwarf virus has traditionally been depicted as disease progress curves which represent an integration of the interactions between virus, host plant and vector.
Francos-Rodriguez, J. C. +3 more
core +1 more source
Journal of Advances in Modeling Earth Systems, 2019 The representation of orographic drag remains a major source of uncertainty for numerical weather prediction (NWP) and climate models. Its accuracy depends on contributions from both the model grid‐scale orography and the subgrid‐scale orography (SSO ...
Andrew D. Elvidge +9 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source