Results 251 to 260 of about 6,473,918 (315)

How mistrust emerged in real time in the Bundibugyo virus disease outbreak: 'Ebola business', social media and the history of mistrust in Ebola epidemics in eastern Congo. [PDF]

BMJ Glob Health
Park SJ, Nguyen VK, Dz'bo FL, Bachweki Basia E, Muhindo Wema K, Mumbesa G, Doevenspeck M, Villa J, Mwanabiningo NM.   +8 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Multiplexing in networks and diffusion. [PDF]

Proc Natl Acad Sci U S A
Chandrasekhar AG, Chaudhary V, Golub B, Jackson MO.   +3 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Empirical-Null Calibration Challenges Comparative CNS Safety Signals for Androgen-Receptor Pathway Inhibitors: A FAERS Re-Analysis. [PDF]

Pharmaceuticals (Basel)
İnkaya A, Güngör HS.
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Lasker~Bloomberg Public Service Award to Michael J. Fox: The challenge of Parkinson's disease. [PDF]

Proc Natl Acad Sci U S A
Schekman R.
europepmc   +1 more source

Two-Dimensional Eye Movement Characteristics of Infantile Nystagmus in Eccentric Gaze. [PDF]

Invest Ophthalmol Vis Sci
Amiebenomo OM, Dunn MJ, McIlreavy L, Erichsen JT, Woodhouse JM.   +4 more
europepmc   +1 more source

Battling bluetongue. [PDF]

Vet Rec
Jarvis S.
europepmc   +1 more source