Results 261 to 270 of about 745,809 (314)

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Multimodal data integration to determine viral and innate immune kinetics in human airway epithelium. [PDF]

open access: yesPLoS Comput Biol
Lukas P   +6 more
europepmc   +1 more source

Comparative Analysis of Intravitreal Diffusion Patterns Across Ex Vivo Human and In Vivo/Ex Vivo Animal Models. [PDF]

open access: yesInvest Ophthalmol Vis Sci
Ayalon A   +8 more
europepmc   +1 more source

Yellow fever outbreak potential in Djibouti, Somalia and Yemen: a mathematical modelling study. [PDF]

open access: yesBMC Glob Public Health
Fraser K   +5 more
europepmc   +1 more source

The inheritance of light. [PDF]

open access: yesPalliat Support Care
Rajendran T.
europepmc   +1 more source

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