Results 101 to 110 of about 295,453 (235)

An astro-neural-field model with application to cortical spreading depolarization

We present a novel astro-neural-field population model with application to migraine-related cortical spreading depolarization. The model is composed of four spatio-temporal state variables: excitatory and inhibitory membrane potentials, astrocytic ...
Mantegazza, M, Nouveau, C, Baspinar, E, Avitabile, D, Desroches, M, Campillo, F   +5 more
core   +5 more sources

Wearable Electro‐Thermal Haptic Stimulator Driven by a Self‐Powered Tactile Sensor for Realistic Stimulus Replication

Advanced Science, EarlyView.
We present a stimulus‐replicating system combining a tactile sensor with a wearable Peltier thermotactile module and concentric electrotactile electrode. Signals encoding pressure and temperature drive the stimulators to reproduce mechano‐thermal cues on the skin. AlN/PDMS encapsulation and SA/LA PSA ensure mechanical compliance and thermal efficiency.
Ey‐In Lee, Chae‐Young Kang, Kyuhyun Hwang, Jongbaeg Kim, Jin‐Woo Park   +4 more
wiley   +1 more source

Neurovascular Effects of Seizure and Cortical Spreading Depolarization Imaged with Widefield Optical Imaging

Neurovascular coupling variation in cortical spreading depolarization may be a key to understanding the origin of neurologic injury. We imaged mice with widefield optical imaging through seizure induction, cortical spreading depolarization, and eventual ...
Humberto Mestre-Payne, Hayden Fisher, Brian R. White, Alyssa Palmucci, Ethan Golberg   +4 more
core   +1 more source

ABCABC Stacking‐Enabled Non‐Centrosymmetry 3R‐ZnIn2S4 Nanosheets for Piezocatalytic Uranium Extraction

Advanced Science, EarlyView.
The ABCABC stacking sequence in 2D ZnIn2S4 nanosheets creates intrinsic non‐centrosymmetry, enabling robust piezocatalysis under weak mechanical agitation. The nanosheets achieve a H2O2 yield of 276.7 µmol g−1 h−1 and uranium extraction capacity of 763.2 mg g−1 via a dual mechanism of direct piezoreduction and in situ H2O2 complexation.
Song Li, Huaijuan Zhou, Yingting Yang, Yanhong Lv, Zdeněk Sofer, Jianyun Zheng, Jinhua Li   +6 more
wiley   +1 more source

Volatile ZrO2 Antiferroelectric Tunnel Junctions for Rapid, Energy‐Efficient Physical Reservoir Computing

Advanced Science, EarlyView.
An antiferroelectric tunnel junction serves as a reservoir computing node, where field‐induced phase transitions and spontaneous ZrO2 relaxation deliver nonlinear fading memory. An In‐Ga‐Zn oxide interlayer enlarges the memory margin and multibit state richness.
Taegyu Kwon, Moonseek Jeong, Su In Hwang, Geun Hyeong Park, Joonyong Kim, Hyojun Choi, Hyeong Seok Choi, Da Hyun Kim, Dong Hee Han, Ju Yong Park, Seungho Baek, Jung Ho Yoon, Dong Hyun Lee, Min Hyuk Park   +13 more
wiley   +1 more source

Focal brain cooling suppresses spreading depolarization and reduces endothelial nitric oxide synthase expression in rats

IBRO Neuroscience Reports
This study aimed to investigate the effects of focal brain cooling (FBC) on spreading depolarization (SD), which is associated with several neurological disorders.
Yuya Hirayama, Hiroyuki Kida, Takao Inoue, Kazutaka Sugimoto, Fumiaki Oka, Satoshi Shirao, Hirochika Imoto, Sadahiro Nomura, Michiyasu Suzuki   +8 more
doaj   +1 more source

Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia

Advanced Science, EarlyView.
Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li, Ying Liu, Longsheng Xing, Xianliang Huang, Yingming Sun, Lei Yue, Yuze Zhang, Huilong Du, Bing Chen   +8 more
wiley   +1 more source

Multifunctional Manganese Oxide Nanocomposite Hydrogel With Synergistic Reactive Oxygen Species‐Scavenging, Oxygen‐Generating, Immunomodulatory, and Photothermal Antimicrobial Activities for Enhanced Diabetic Wound Healing

Advanced Science, EarlyView.
CFP/PC@MnO2 hydrogel integrates ROS scavenging, oxygen delivery, oxidative stress reduction, immunomodulation, and photothermal antibacterial properties. The incorporation of PC@MnO2 NPs endows the hydrogel with multiple functional advantages tailored to the pathological microenvironment of diabetic wounds, including efficient ROS clearance, mitigation
Zhi Xu, Xiaodong Luo, Jingxian Wu, Chaoyang Huang, Zhuoying Yang, Yixiang HePeng, Bosong Zhou, Xiang Li, Ruiyuan Liu, Xu Wu   +9 more
wiley   +1 more source

Adenosine Receptor Activation in Spreading Depolarization and Ischemic Injury

, 2017
Spreading depolarization (SD) is a propagating wave of neuronal activation occurring in the central nervous system. SD is accompanied by depression of synaptic activity and complex blood flow changes.
Lindquist, Britta E
core  

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

Advanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li, Xiao‐Bo Qian, Hai‐Long Zhang, Di Li, Ling Ji, Xin‐Chun Xu, Jia‐Sheng Ding, Li‐Jun Yin, Li Zhang, Guang‐Yin Xu, Rong Gao   +10 more
wiley   +1 more source