Results 101 to 110 of about 4,203,928 (297)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Rebuilding a community: lessons from New Orleans [PDF]
Whether low-income communities are struggling to rebuild after a hurricane or after long neglect, the challenges often seem insurmountable. The New Orleans 9th Ward’s inclusive approach to decision making shows that the best revitalization plans are ...
Kenneth M. Reardon
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Starting a community development bank: a New Haven story [PDF]
With their ability to attract socially conscious investors to a community bank and provide tax deductions, nonprofits could become increasingly pivotal in making financial services available to low- and moderate-income communities.Community banks ...
Peggy Delinois Hamilton
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Deconstructing the myths: housing development versus school costs [PDF]
William Ray of the New Hampshire Housing Finance Authority analyzes the connection between housing development and accelerating public school spending in the Granite State.Housing - Prices - New Hampshire ; Economic conditions - New Hampshire ; Education
William Rey
core
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
, 1910 A doctor and a naturalist, Charles Townsend spent May-June 1909 travelling through Labrador. Although his primary interest was ornithology, his book devotes chapters to trees and rivers, as well as the Aboriginal Peoples and Acadian settlers he encountered. ; Includes bibliographical references and index.
openaire +4 more sources
Measuring cultural vitality in communities [PDF]
Until recently, arts and culture data collected as part of urban revitalization planning focused on large institutions. The Urban Institute’s Arts and Culture Indicators Project provides a richer understanding of communities’ cultural strength and how it
Maria Rosario Jackson
core
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source