Results 111 to 120 of about 2,146,528 (354)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

NEXUS Spring Institute Program [PDF]

open access: yes, 2006
Provides an overview of the 2006 NEXUS Spring Institute New Frontiers in Health Behaviour: Understanding Place and Space, and abstracts where available.Applied Science, Faculty ofNursing, School ...
University of British Columbia. NEXUS Research Unit
core  

On the Beach in Spring Lake [PDF]

open access: yes, 2011
If you are looking for a spot to put up a tent, bring your food and beer to the beach and listen to your music, Spring Lake is not for you.
Beards, Daniel E.
core   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Tucker Center Newsletter Spring 1998 [PDF]

open access: yes, 1998
Spring 1998 NewsletterTucker Center. (1998). Tucker Center Newsletter Spring 1998.
Tucker Center
core  

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Tucker Center Newsletter Spring 2014 [PDF]

open access: yes, 2014
Spring 2014 NewsletterTucker Center. (2014). Tucker Center Newsletter Spring 2014.
Tucker Center
core  

Assessment of water resources contamination in the Qatrouyeh National Park, Fars [PDF]

open access: yesاکولوژی انسانی
In the wildlife habitat management, maintaining water quality and quantity, especially in the arid ecosystems of Iran that are faced to relative limitations and dryness tension of water resources is one of the planning fundament in conserving wildlife ...
Pejman Khaksar Boldaji, Haniyeh Nowzari
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Tucker Center Newsletter Spring 2007 [PDF]

open access: yes, 2007
Spring 2007 NewsletterTucker Center. (2007). Tucker Center Newsletter Spring 2007.
Tucker Center
core  

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