Results 21 to 30 of about 55,183 (266)

Research on the Seismic Isolation Effect of the Ring Spring–Friction Pendulum Bearing in the Dakai Underground Subway Station

open access: yesApplied Sciences, 2023
During strong earthquakes, the vertical seismic force becomes an essential factor affecting shallow underground structures that cannot be ignored. In this situation, it is proposed that ring spring–friction pendulum two-way seismic isolation bearings be ...
Jie Zhang, Jie Jia
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben   +4 more
wiley   +1 more source

Research on Piston Dynamics and Engine Performances of a Free-Piston Engine Linear Generator Coupling with Various Rebound Devices

open access: yesEnergies, 2023
Free-piston engine linear generators (FPELGs) are an innovative linear power device that exhibits the distinctive dynamics of pistons and performance of free-piston engines.
Chendong Guo   +5 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Development of a dynamic vibration absorber with adjustment mechanism of spring constant and damping coefficient

open access: yesNihon Kikai Gakkai ronbunshu
This paper proposes a simple passive device with an adjustment mechanism for spring constant and damping coefficient to realize a dynamic vibration absorber (DVA) that can be used for various vibration control target frequencies.
Manaya NAITO   +2 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

DETERMINATION OF CHARACTERISTICS OF THROTTLING DEVICE FOR PNEUMATIC SPRING

open access: yesNauka ta progres transportu, 2018
Purpose. This paper focuses on determination of the dependence of the working medium flow on the capacity of the throttling device, its geometric features and the pressure difference in the pneumatic spring cylinder and in the auxiliary reservoir ...
O. H. Reidemeister, A. V. Laguza
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

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