Results 31 to 40 of about 55,183 (266)

Development of a Stacking Device for Medical Urine Cups

open access: yesJournal of Pharmacy and Bioallied Sciences
The study focuses on creating a stacking device for medical urine cups, integrating pressing, storing, and collecting mechanisms to streamline palletizing without manual intervention. This approach enhances efficiency and reduces costs.
Zhao Peng, Farra A. Jumuddin
doaj   +1 more source

3D modeling design and engineering analysis of automotive suspension beam

open access: yesMATEC Web of Conferences, 2016
Automotive suspension is an important device for transmission and torque. The main parameters and dimensions of 40 tons of heavy duty truck spring suspension system are designed in the paper. According to the data, the 3D modeling and virtual assembly of
Ju Zhi Lan   +3 more
doaj   +1 more source

Mechanical Devices of the Spliceosome: Motors, Clocks, Springs, and Things [PDF]

open access: yesCell, 1998
We thank J. Thorner, J. Lorsch, and D. Herschlag for provocative discussions; J. Abelson, R. Luhrmann, T. Nilsen, and R. Reed for preprints; and G. Chanfreau, C. Collins, A. Frankel, A. Kistler, K. Lynch, S. Rader, B. Raumann, D. Ryan, C. Siebel, J. Wagner, Y. Wang, J.
Staley, Jonathan P, Guthrie, Christine
openaire   +2 more sources

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

A Compact Cardiopulmonary Resuscitation Chest Compression Device Using a Torsion-Based Series Elastic Actuator

open access: yesIEEE Access
Cardiopulmonary Resuscitation (CPR) is crucial in emergency cardiac arrest situations. To reduce paramedic fatigue and ensure steady CPR performance, automated chest compression devices have been developed.
Sungmoon Hur   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Three-dimensionally printed surface features to anchor endoluminal spring for distraction enterogenesis. [PDF]

open access: yesPLoS ONE, 2018
Spring-mediated distraction enterogenesis has been studied as a novel treatment for short bowel syndrome (SBS). Previous approaches are limited by multiple surgeries to restore intestinal continuity.
Nhan Huynh   +9 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy