Results 51 to 60 of about 5,132,390 (317)
Development of a Stacking Device for Medical Urine Cups
Journal of Pharmacy and Bioallied SciencesThe study focuses on creating a stacking device for medical urine cups, integrating pressing, storing, and collecting mechanisms to streamline palletizing without manual intervention. This approach enhances efficiency and reduces costs.
Zhao Peng, Farra A. Jumuddin
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3D modeling design and engineering analysis of automotive suspension beam
MATEC Web of Conferences, 2016 Automotive suspension is an important device for transmission and torque. The main parameters and dimensions of 40 tons of heavy duty truck spring suspension system are designed in the paper. According to the data, the 3D modeling and virtual assembly of
Ju Zhi Lan +3 more
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Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
IEEE AccessCardiopulmonary Resuscitation (CPR) is crucial in emergency cardiac arrest situations. To reduce paramedic fatigue and ensure steady CPR performance, automated chest compression devices have been developed.
Sungmoon Hur +4 more
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Three-dimensionally printed surface features to anchor endoluminal spring for distraction enterogenesis. [PDF]
PLoS ONE, 2018 Spring-mediated distraction enterogenesis has been studied as a novel treatment for short bowel syndrome (SBS). Previous approaches are limited by multiple surgeries to restore intestinal continuity.
Nhan Huynh +9 more
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FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Design and Strength Safety Analysis of Pressure Relief Device for Perforating Gun
Shiyou jixiePerforation detonation produces high-temperature and high-pressure gas. If the pressure exceeds the internal pressure strength of the gun body， the perforating gun would break， leading to accidents such as gun expansion and jamming.
Li Mingfei +6 more
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FEBS Open Bio, EarlyView.What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman +4 more
wiley +1 more source