Results 91 to 100 of about 55,210 (284)

The guidelines of asthma: the boon and the bane

Egyptian Journal of Chest Disease and Tuberculosis, 2018
This article is a small piece of mind intended to scrutinize the international asthma guidelines with a sprinkle of subtle criticism toward standard guidelines. As aspiring doctors, we must not always merely adopt international standards, but always stay
Gamal Abdelrahman
doaj   +1 more source

Proposed dynamic phase difference method for the detection of tile debonding from the space shuttle orbiter [PDF]

A noncontracting, semi-global, dynamic technique was developed for detecting loose tiles on the space shuttle orbiter. In laboratory tests on a single tile, the substrate was excited into lateral motion at a constant frequency and amplitude of 2g.
Sprinkle, D. R., Zuckerwar, A. J.
core   +1 more source

Cooking for Ohio Families [PDF]

, 1948
PDF pages ...
Garvin, Alma L., Gerlaugh, Mary E., Green, Eloise, Hughes, Osee   +3 more
core  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Forma funcional para las ecuaciones comerciales de Estados Unidos y México

Estudios Económicos, 1997
La literatura relacionada con los flujos de comercio bilateral entre México y Estados Unidos es comparativamente pequeña. Con la importancia creciente del comercio entre estas economías, las respuestas potenciales del flujo de comercio ante cambios en ...
Thomas M. Fullerton Jr., W. Charles Sawyer, Richard L. Sprinkle   +2 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Development of ZYBG type automatic explosion suppression device of mine-used gas transmission pipeline

Gong-kuang zidonghua, 2014
ZYBG type automatic explosion suppression device of mine-used gas transmission pipeline was developed by use of active explosion suppression technology in order to guarantee safety of the gas transmission pipeline.
RONG Jia, HU Shuangqi, ZHOU Wen, TIAN Danqing   +3 more
doaj   +1 more source

Top and side gated epitaxial graphene field effect transistors

, 2009
Three types of first generation epitaxial graphene field effect transistors (FET) are presented and their relative merits are discussed. Graphene is epitaxially grown on both the carbon and silicon faces of hexagonal silicon carbide and patterned with ...
Berger, Berger, Bostwick, Dawlaty, Devine, dos Santos, Faugeras, Filleter, Gu, Hass, Hass, Kedzierski, Martin, Miller, Moon, Novoselov, Orlita, Rollings, Ryu, Shon, Sun, Wu, Zhang, Zhang   +23 more
core   +1 more source