Results 101 to 110 of about 55,210 (284)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Russia in the global hydrocarbon economy

open access: yesRUDN Journal of Economics, 2018
“Russia is a world gas column or a world kerosene”. These slogans are widely used in anti-Russian rhetoric, especially by those opponents who, giving them a pejorative character, try to show the innovative backwardness of our “resource” economy in ...
S N Lavrov, B G Dyakin
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Long road to Sprinkles [PDF]

open access: yesCanadian Medical Association Journal, 2009
Dr. Stanley Zlotkin’s invention was never going to be a money-maker. After all, it was designed to combat the debilitating iron deficiency experienced by children in the developing world. Not a lot of purchasing power there.
openaire   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Antioxidant compounds in Salvia officinalis L. shoot and hairy root cultures in the nutrient sprinkle bioreactor

open access: yesActa Societatis Botanicorum Poloniae, 2011
The study focused on the production of compounds with antioxidant activity in hairy root and shoot cultures of Salvia officinalis grown in laboratory-scale sprinkle nutrient bioreactors.
Izabela Grzegorczyk, Halina Wysokińska
doaj   +1 more source

Impact of the Belding's ground squirrel, Spermophilus beldingi, on alfalfa production in northeastern California [PDF]

open access: yes, 1984
The Belding ground squirrel (Spermophilus beldingi) is found in rangeland, pasture, and various agronomic crops. However, its impact on agricultural production has been measured only rarely, e.g., by Grinnell and Dixon (1918) and Sauer (1976, 1977).
Sauer, Warren C.
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

A comparison of turbulent CFD with Gaussian dispersion models on a methane emission test site

open access: yesAtmospheric Environment: X
This article investigates the influence of structures on the atmospheric transport of methane in an outdoor industrial environment, and provides a comparison in the predictive capability of Gaussian dispersion models against a turbulent computational ...
Ryker Fish   +3 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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