Results 41 to 50 of about 13,339 (340)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Mixture toxicity, cumulative risk, and environmental justice in United States federal policy, 1980–2016

open access: yesEnvironmental Health, 2021
Toxic chemicals — “toxicants” — have been studied and regulated as single entities, and, carcinogens aside, almost all toxicants, single or mixed and however altered, have been thought harmless in very low doses or very weak concentrations. Yet much work
Robert Hunt Sprinkle   +1 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Pemberian taburia (sprinkle) berpengaruh terhadap lama dan frekuensi diare akut anak

open access: yesJurnal Gizi Klinik Indonesia, 2013
Background: Major causes of mortality in children are diarrhea and pneumonia (25.2% and 15.5%). “Five steps of diarrhea management” is an integrated approach in the management of diarrhea comprising the supplementation of oral rehydration, zinc within 10
Sopiyandi Sopiyandi   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

APPLICATION OF POTASSIUM NUTRITION SUPPLY TO SHALLOT PLANTS UNDER SMART K – SPRINKLE FERTIGATION IN DRY LAND

open access: yes, 2020
The purpose of this study was to investigate smart k – sprinkle fertigation in dry land with potassium nutrition supply on growth and yield of shallot plants.
Sari, Mona   +4 more
core   +1 more source

Solar-Based Fuzzy Intelligent Water Sprinkle System

open access: yesJournal of Mechatronics, Electrical Power, and Vehicular Technology, 2012
A solar-based intelligent water sprinkler system project that has been developed to ensure the effectiveness in watering the plant is improved by making the system automated.
Riza Muhida   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Letter from Joe Sprinkle, Jr. to Oscar Monnig

open access: yes, 1957
Letter from Joe Sprinkle, Jr.
Sprinkle, Joe F., Jr.
core   +1 more source

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