Results 51 to 60 of about 13,339 (340)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Iowa's Experience with Sprinkle Treatment of Asphalt Pavements, Progress Report for Project HR-199, July 1982 [PDF]
, 1982 The practice of sprinkle treating asphalt surfaces with high-quality aggregate to provide improved frictional characteristics has been used in Europe since the 1960s.
core +2 more sources
Topiramate sprinkle is effective in the treatment of childhood epilepsy [PDF]
Universa Medicina, 2012 Background Epilepsy remains one of the most frequently occurring pediatric problems. Approximately 10-15% patients do not respond to conventional therapy.
Prastiya Indra Gunawan, Darto Saharso
doaj
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Linear Algebra and its Applications, 1993 The authors define a sprinkling to be a matrix-valued linear function \(W(x)\) of a vector variable \(x\) with the property that every nonzero entry of \(W(x)\) is an entry of \(x\). The sprinkling problem is to characterize those sprinklings \(W\) for which \(N(W(x)) \leq n(x)\) for all \(x\), where \(N\) denotes the spectral norm for matrices and \(n\
Johnson, Charles R., Nylen, Peter M.
openaire +2 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Crinoid ancestry without blastozoans [PDF]
Acta Palaeontologica Polonica, 2016 At present, a debate in the paleontologic literature focuses on whether or not the immediate ancestry of the Crinoidea lies in an unidentified member of the Blastozoa, which includes eocrinoids and an assemblage known variously as the “cystoids”.
Thomas E. Guensburg +3 more
doaj +1 more source
The urge to sprinkle statistics is irresistible [PDF]
BMJ, 2007 Reading the article by Glasziou et al, we might be forgiven for believing that they had discovered some hitherto unknown method of causal inference.1 Instead, of course, they have merely stumbled across the way in which causes have been identified in everyday life and science throughout …
openaire +2 more sources
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source