Results 171 to 180 of about 17,559 (273)

Physiologically Based Pharmacokinetic Modeling to Characterize the Disposition of Topiramate in Children with and without Obesity

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 10, October 2026.
Abstract Topiramate (TPM) is used to treat seizures in adults and children ≥2 years. In children, TPM dosing is body weight based. It is unknown whether children with obesity may benefit from an alternative dosing strategy. We developed a novel physiologically based pharmacokinetic (PBPK) model for TPM that accounts for age‐ and obesity‐related changes
Patricia D. Maglalang   +14 more
wiley   +1 more source

Evaluation of a novel laser‐system operating at 1940 nm for weed control and determining the influence of biological and operational factors

open access: yesPest Management Science, Volume 82, Issue 10, Page 10428-10438, October 2026.
The control efficacy of a novel laser pulse system operating at 1940 nm was tested. The new system allows effective control of young weeds with 1.5 J. Targeting the plant stem is 53‐fold more energy‐efficient than the meristem. Species morphology and beam diameter significantly influence weed control efficacy. Abstract BACKGROUND This study evaluates a
Ran Nisim Lati   +6 more
wiley   +1 more source

Patterns and Drivers of Mercury Accumulation in Croplands, a Meta‐Analysis

open access: yesJournal of Geophysical Research: Biogeosciences, Volume 131, Issue 10, October 2026.
Abstract Mercury (Hg) is a potent neurotoxin that poses risks to human and environmental health, particularly in regions influenced by anthropogenic Hg emissions. Although Hg emissions have declined across North America and Europe following regulatory controls and phase‐outs, emissions remain elevated in some regions due to activities such as artisanal
Jenna M. Hynes   +2 more
wiley   +1 more source

Inferring Adaptation at Community Composition Level From the Relationship Between Succession Rate and Global Change Intensity

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 5, October 2026.
A 10‐year nitrogen addition experiment in Eurasian steppe reveals that plant and microbial community succession rates first increase then decrease with rising N intensity, indicating an adaptive threshold. Deterministic processes driven by soil physicochemical changes dominate this response, with management strategies modulating adaptation via ...
Tingting Li   +3 more
wiley   +1 more source

From Reactive Remediation to Predictive Prevention: A Systems Synthesis of Global Soil Salinization and Sodicity

open access: yesGlobal Change Biology, Volume 32, Issue 10, October 2026.
Salty soils are spreading across the world's farmland, often building up unnoticed for years before crop yields fall sharply and repair becomes slow and costly. Our review shows that this damage comes from linked problems in soil chemistry, water management, and policy, so fixing any one of them alone rarely works.
Matthew D. Wallenstein   +3 more
wiley   +1 more source

Beyond the Law: A Qualitative Socio‐Ecological Study of Substance Use Treatment Barriers and Adaptations in Ghana

open access: yesJournal of Psychiatric and Mental Health Nursing, Volume 33, Issue 5, Page 766-779, October 2026.
ABSTRACT Background Ghana's response to substance use has long been dominated by criminalisation, yet limited research has examined how this policy environment shapes addiction treatment delivery. This study explored the perspectives of mental health nurses providing care to people who use drugs (PWUDs) using a socio‐ecological framework.
Evans F. Kyei   +4 more
wiley   +1 more source

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