Results 61 to 70 of about 226,094 (387)

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

FEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke, Nils Alexander Lakomek, Georg Groth   +2 more
wiley   +1 more source

Patient and Public Involvement (PPI) and Responsible Research and Innovation (RRI) approaches in mental health projects involving young people: a scoping review protocol

Research Involvement and Engagement
Background Rather than being perceived as merely ‘part of the problem’, the perspectives and experiences of young people play a pivotal role in devising effective solutions for mental health challenges.
Josimar Antônio de Alcântara Mendes, Mathijs Lucassen, Alex Adams, Lucy Martin, Christine Aicardi, Rebecca Woodcock, Emma Nielsen, Ellen Townsend, Marina Jirotka   +8 more
doaj   +1 more source

Positive and negative regulation of angiogenesis by soluble vascular endothelial growth factor receptor-1 [PDF]

, 2018
Vascular endothelial growth factor receptor (VEGFR)-1 exists in different forms, derived from alternative splicing of the same gene. In addition to the transmembrane form, endothelial cells produce a soluble VEGFR-1 (sVEGFR-1) isoform, whereas non ...
Carbo, Miriam, Failla, Cristina M., Morea, Veronica   +2 more
core   +2 more sources

Is Mossy Fiber Sprouting a Potential Therapeutic Target for Epilepsy?

Frontiers in Neurology, 2018
Mesial temporal lobe epilepsy (MTLE) caused by hippocampal sclerosis is one of the most frequent focal epilepsies in adults. It is characterized by focal seizures that begin in the hippocampus, sometimes spread to the insulo-perisylvian regions and may ...
C. Cavarsan, J. Malheiros, C. Hamani, I. Najm, L. Covolan   +4 more
semanticscholar   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Effects of Thermal and Non-Thermal Pre-Processing Methods on Physical Parameters of Jack bean (Canavalia ensiformis) Seed

Journal of Applied Sciences and Environmental Management, 2018
Effects of thermal and non-thermal pre-processing methods on the physical parameters of jackbean seed were investigated. The bean was subjected to three pre-processing methods roasting and autoclaving which are thermal and sprouting a non-thermal pre ...
JO Odedeji, EA Akande, OO Fapojuwo, A Ojo   +3 more
doaj   +1 more source

Dormancy in reproductive vegetative buds in creeping perennials dominating the agricultural weed flora in Scandinavia [PDF]

, 2013
Dormancy, which is the inability to initiate normal growth under otherwise favourable conditions, is an adaptation to escape sprouting prior to seasonal cold temperatures and/or drought in areas where winters are harsh or summers dry.
Liew, Josefine
core  

Differential coupling of gibberellin responses by Rht-B1c suppressor alleles and Rht-B1b in wheat highlights a unique role for the DELLA N-terminus in dormancy [PDF]

, 2017
During the Green Revolution, substantial increases in wheat (Triticum aestivum) yields were realized, at least in part, through the introduction of the Reduced height (Rht)-B1b and Rht-D1b semi-dwarfing alleles.
Chandler, Peter Michael, Rohde, Antje, Van De Velde, Karel, Van Der Straeten, Dominique   +3 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Impact of Selected Storage Methods on Physical Properties of Potato (Solanum tuberosum L.) Tuber

Turkish Journal of Agriculture: Food Science and Technology
Potatoes are starchy tubers consumed as staples in most parts of the world. Its storage is critical in preserving tuber quality, reducing post-harvest losses, and ensuring food security.
Thomas Okache, Olayinka R. Karim, Adegbola O. Dauda   +2 more
doaj   +1 more source