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Current Treatment Options in Gastroenterology, 2004
Tropical sprue is a disease that causes progressive villus atrophy in the small intestine, similar to nontropical (celiac) sprue. The loss of intestinal villi profoundly affects intestinal absorptive function, and patients with tropical or nontropical sprue present with malabsorption.
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Tropical sprue is a disease that causes progressive villus atrophy in the small intestine, similar to nontropical (celiac) sprue. The loss of intestinal villi profoundly affects intestinal absorptive function, and patients with tropical or nontropical sprue present with malabsorption.
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Current Gastroenterology Reports, 2005
Tropical sprue (TS) is a clinical entity of unknown etiology characterized by an acquired chronic diarrheal illness and malabsorption that affects indigenous inhabitants and expatriates, either long-term residents or short-term visitors, in the tropical countries. The exact pathogenetic sequence of TS remains incompletely characterized.
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Tropical sprue (TS) is a clinical entity of unknown etiology characterized by an acquired chronic diarrheal illness and malabsorption that affects indigenous inhabitants and expatriates, either long-term residents or short-term visitors, in the tropical countries. The exact pathogenetic sequence of TS remains incompletely characterized.
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Journal of the American Medical Association, 1923
Of forty-five cases of tropical sprue occurring in India, Leonard Rogers1reports a probable cure in only one, and no material improvement in twenty-six. Tropical sprue may be considered, therefore, a very serious nutritional and diarrheal disease. Nearly all the patients seen in the New York district have acquired and developed the disease in some ...
WALTER A. BASTEDO, L. W. FAMULENER
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Of forty-five cases of tropical sprue occurring in India, Leonard Rogers1reports a probable cure in only one, and no material improvement in twenty-six. Tropical sprue may be considered, therefore, a very serious nutritional and diarrheal disease. Nearly all the patients seen in the New York district have acquired and developed the disease in some ...
WALTER A. BASTEDO, L. W. FAMULENER
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The Lancet, 1986
In 27 Puerto Rican patients with tropical sprue proven by intestinal biopsy and clinical response to folic acid, HLA type was determined with a microcytotoxicity assay. 25 of these patients had at least one antigen of the Aw-19 series (p = 10(-10)). The strongest association was with Aw-31, for which the relative risk was 10.6 (p = 1.2 X 10(-6)).
R, Menendez-Corrada +2 more
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In 27 Puerto Rican patients with tropical sprue proven by intestinal biopsy and clinical response to folic acid, HLA type was determined with a microcytotoxicity assay. 25 of these patients had at least one antigen of the Aw-19 series (p = 10(-10)). The strongest association was with Aw-31, for which the relative risk was 10.6 (p = 1.2 X 10(-6)).
R, Menendez-Corrada +2 more
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Southern Medical Journal, 1930
According to Osler, it is difficult to classify sprue, as various views of its etiology are held. It is a disease of tropical or subtropical countries, more often occurring in the newcomer and in the better class of people. The disease is characterized by a distinctive sore tongue and mouth, a peculiar type of diarrhea, marked anemia, loss of weight ...
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According to Osler, it is difficult to classify sprue, as various views of its etiology are held. It is a disease of tropical or subtropical countries, more often occurring in the newcomer and in the better class of people. The disease is characterized by a distinctive sore tongue and mouth, a peculiar type of diarrhea, marked anemia, loss of weight ...
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Immunoglobulins in Tropical Sprue
Scandinavian Journal of Gastroenterology, 1970Samuel, A. M., Singh. B. & Jarnum, S. 1970. Immunoglobulins in Tropical Sprue. Scand. J. Gastroent.
A M, Samuel, B, Singh, S, Jarnum
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The Journal of Pediatrics, 1970
Eleven Puerto Rican children with chronic diarrhea, intestinal malabsorption, abnormal jejunal mucosa, megaloblastic bone marrow, and malnutrition have been studied. The patients were treated with folic acid alone or folic acid and vitamin B 12 ; one patient received oxytetracycline.
P J, Santiago-Borrero +2 more
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Eleven Puerto Rican children with chronic diarrhea, intestinal malabsorption, abnormal jejunal mucosa, megaloblastic bone marrow, and malnutrition have been studied. The patients were treated with folic acid alone or folic acid and vitamin B 12 ; one patient received oxytetracycline.
P J, Santiago-Borrero +2 more
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Annals of Internal Medicine, 1966
Excerpt The first description of tropical sprue was presented over 2 centuries ago by Hillary from the island of Barbados in the West Indies (1, 2).
F A, Klipstein +2 more
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Excerpt The first description of tropical sprue was presented over 2 centuries ago by Hillary from the island of Barbados in the West Indies (1, 2).
F A, Klipstein +2 more
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Presse medicale (Paris, France : 1983), 2007
Tropical sprue associates prolonged diarrhea, a malabsorption syndrome, and nutritional deficiency in patients who live in or have visited tropical areas. Pathogenesis is still unknown but an infectious cause is suspected. Macrocytic anemia and hypoalbuminemia are present, together with progressive villus atrophy of the small intestine.
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Tropical sprue associates prolonged diarrhea, a malabsorption syndrome, and nutritional deficiency in patients who live in or have visited tropical areas. Pathogenesis is still unknown but an infectious cause is suspected. Macrocytic anemia and hypoalbuminemia are present, together with progressive villus atrophy of the small intestine.
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British Journal of Haematology, 1972
Summary. Persons who acquire tropical sprue lose their ability to absorb folate from the diet. This is due to inability to hydrolyse polyglutamate forms in most cases and additionally to absorb monoglutamate folate in instances of severe mucosal damage.
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Summary. Persons who acquire tropical sprue lose their ability to absorb folate from the diet. This is due to inability to hydrolyse polyglutamate forms in most cases and additionally to absorb monoglutamate folate in instances of severe mucosal damage.
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