Results 91 to 100 of about 55,433 (255)

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva   +23 more
wiley   +1 more source

Tsc3 regulates SPT amino acid choice in Saccharomyces cerevisiae by promoting alanine in the sphingolipid pathway

open access: yesJournal of Lipid Research, 2018
The generation of most sphingolipids (SPLs) starts with condensation between serine and an activated long-chain fatty acid catalyzed by serine palmitoyltransferase (SPT).
Jihui Ren   +8 more
doaj   +1 more source

Repeated Pleistocene Permafrost Episodes in the Western Pannonian Basin

open access: yesPermafrost and Periglacial Processes, EarlyView.
ABSTRACT Concerning the study of past periglacial processes, the Pannonian Basin is a key area as it contains the southernmost frost polygons found in Central Europe. The presence or absence of permafrost is still, however, a matter of debate, and data on the timing of frost action are also scarce.
Krisztina Sebe   +5 more
wiley   +1 more source

PEMBETULAN SPT TERKAIT KESESUAIAN DATA PELAPORAN SPT TAHUNAN DAN SPT MASA PPN

open access: yes, 2023
Data dan informasi yang dilaporkan dalam SPT Tahunan Badan harus bersesuaian dengan data di SPT Masa PPN. Jika ditemukan ketidaksesuaian maka wajib pajak akan menerima SP2DK untuk memberikan tanggapan dan penjelasan.
MAHARANI, MARETTA AURA SAKTI
core   +1 more source

Polymersome‐Enabled Multimodal Delivery of Tobramycin and Doripenem for Targeted Eradication of Pseudomonas aeruginosa Biofilms in Chronic Rhinosinusitis

open access: yesSmall, EarlyView.
Schematic representation of diffusion‐based versus pH‐triggered drug release within a bacterial biofilm. In diffusion‐based systems, drug cargo is gradually released independent of local pH, resulting in rapid burst release and reduced sustained concentrations.
Amalie Kjær Andresen   +9 more
wiley   +1 more source

Three‐Dimensional Optical and Computational Reconstruction of Colloidal Electrokinetic Flows via Multiplane Imaging and Multiscale Modeling

open access: yesSmall, EarlyView.
Fast 3D multiplane microscopy is combined with multiscale electrokinetic modeling to reconstruct nanoparticle motion around quadrupolar electrodes. This integrated optical‐computational framework reveals the full three‐dimensional structure of colloidal electrokinetic flows, including localized trapping, depletion layers, and complex vortical motion ...
Flip de Jong   +23 more
wiley   +1 more source

Harnessing the nonthermal effects of ultrasound for cancer treatment: From mechanisms to applications

open access: yesSmart Molecules, EarlyView.
Nonthermal ultrasound transforms acoustic energy into diverse therapeutic bioeffects through cavitation, mechanical stimulation, and physicochemical activation. This review discusses how acoustic parameters, biological mechanisms, and responsive materials interact to influence nonthermal ultrasound‐enabled cancer therapies. Mechanism‐guided engineering
Liu Wang   +5 more
wiley   +1 more source

Assessment of Oxidative Stress, Vitellogenin, and Human Health Risks Derived From Nile Tilapia Exposed to Metals and Metalloids in Southeastern Brazil

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Urban coastal lagoons are highly vulnerable ecosystems increasingly affected by metal contamination, as well as multiple anthropogenic stressors. This study evaluated ecotoxicological and human health risks associated with chronic metal exposure in Nile tilapia (Oreochromis niloticus) from an anthropogenically impacted lagoon in southeastern ...
Julia Araújo Alves   +8 more
wiley   +1 more source

Standart Penetrasyon Deneyi (SPT) ile Kartepe (İzmit) Deniz Hava Üs Komutanlığı Hangar İnşaat Alanı Zemininin Sıvılaşma Potansiyelinin Araştırılması

open access: yesDüzce Üniversitesi Bilim ve Teknoloji Dergisi, 2016
Bu çalışma, Kartepe Deniz Hava Üs Komutanlığı (İzmit) bölgesinde askeri amaçla yapılması planlanan hangar inşaatı zemininin jeolojik ve jeoteknik özelliklerini ortaya koymak ve olası bir deprem etkisinde oluşabilecek hasarların önceden tahmin ve ...
Ali Ateş
doaj  

SPT-SZ MCMF: an extension of the SPT-SZ catalogue over the DES region

open access: yes
We present an extension to a Sunyaev-Zel'dovich Effect (SZE) selected cluster catalogue based on observations from the South Pole Telescope (SPT); this catalogue extends to lower signal to noise than the previous SPT-SZ catalogue and therefore includes ...
et al. (7893743)   +17 more
core  

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