Results 151 to 160 of about 805,583 (361)
Introduction: Malignant central airway obstruction (MCAO) is a challenging therapeutic scenario, caused by tumour burden which limits airflow within the large airways. Squamous cell carcinoma (SCC) of the lung accounts for 50% of MCAO seen in the setting
Eoin Collins +2 more
doaj +1 more source
Cervical metastasis after treatment of the oral squamous cell carcinoma
Takatsuna Nakamura +3 more
openalex +2 more sources
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang +7 more
wiley +1 more source
Treatment Outcome of Cervical Cancer Patients at Ocean Road Cancer Institute, Dar es salaam [PDF]
Cervical cancer is the second commonest malignancy in females globally. Cancer of the cervix has a devastating impact on women’s health in developing countries especially Africa since more than 75% of the worldwide burden of the disease occurs in these ...
Majinge, Peter MC
core
Halofuginone is a Molecular Glue Degrader of Integrin β4
Integrin β4 overexpression is linked to aggressive tumors and poor prognosis, but targeted therapies are lacking. We identified halofuginone (HF) as a molecular glue degrader that promotes integrin β4 degradation via the CRL4BWDR18 E3 ligase. HF suppresses tumor progression in vitro and in vivo, offering a new strategy for targeting oncogenic ...
Wei Gong +8 more
wiley +1 more source
Repression of Esophageal Neoplasia and Inflammatory Signaling by Anti-miR-31 Delivery In Vivo. [PDF]
BACKGROUND: Overexpression of microRNA-31 (miR-31) is implicated in the pathogenesis of esophageal squamous cell carcinoma (ESCC), a deadly disease associated with dietary zinc deficiency.
Alder, Hansjuerg +14 more
core +1 more source
Commercial Claims–Based Comparison of Survival and Toxic Effects of Definitive Radiotherapy vs Primary Surgery in Patients With Oropharyngeal Squamous Cell Carcinoma [PDF]
David J. Sher +4 more
openalex +1 more source
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding +10 more
wiley +1 more source

