Results 161 to 170 of about 5,293,476 (246)

KLF4 Promotes a KRT13+ Hillock-Like State in Lung Squamous Cell Carcinoma. [PDF]

Cancer Res
Izzo LT, Reyes T, Meesala S, Ireland AS, Earnest-Noble LB, Yang S, Sunil HS, Cheng XC, Tserentsoodol N, Hawgood SB, Glass C, Patz EF, Witt BL, Tyson DR, O'Donnell KA, Oliver TG.   +15 more
europepmc   +1 more source

Systematic pathway‐level analysis defines conserved transcriptional divergence between primary lung tumors and cell line models

Animal Models and Experimental Medicine, EarlyView.
Lung cancer cell lines diverge substantially from primary tumors at the transcriptional level. Using single‐sample gene set enrichment analysis and L1‐penalized feature selection across TCGA‐LUAD and CCLE‐LUAD, we identified five Hallmark pathways (E2F targets, G2M checkpoint, IFNγ response, coagulation, and EMT) that discriminated primary tumors from ...
Pritam Bera, Rajesh Raju, Debodipta Das
wiley   +1 more source

Zebrafish xenograft models as a fast platform for metastasis diagnosis and cisplatin response of head and neck squamous cell carcinoma

Animal Models and Experimental Medicine, EarlyView.
A zebrafish xenograft model accurately distinguishes metastatic from non‐metastatic HNSCC and recapitulates cisplatin sensitivity/resistance patterns. Using patient‐derived tumors, it predicts individual therapeutic responses, offering a rapid, clinically applicable platform for guiding personalized treatment. Abstract Background Head and neck squamous
Lu Chen, Shu Sun, Yujia Liu, Liehao Jiang, Cuiyun Wu, Ting Liu, Yujiao Zhao, Yuwei Liu, Lu Liu, Qi Wang, Xiaowei Zheng, Ping Huang   +11 more
wiley   +1 more source

Identification of STAT1 as a biomarker for lymph node metastasis in esophageal squamous cell carcinoma. [PDF]

J Mol Histol
Lv G, Li H, Lei Y, Peng J, Liu F, Zhao W.   +5 more
europepmc   +1 more source

Modeling Catheter‐Associated Bladder Mucosal Adhesion and Microtrauma Using a Human Urothelial Microtissue Model

Advanced NanoBiomed Research, EarlyView.
Intermittent catheter use can damage the urinary tract and predispose to infection. We deployed a complex human urothelial model to investigate. Catheter contact induced compressive and shear stress causing umbrella cell disruption, reduced barrier function, inflammation and increased cell adhesion to the catheter surface.
Nazila V. Jafari, Jennifer L. Rohn
wiley   +1 more source

Molecular detection of <i>Leishmania</i> spp. in feline squamous cell carcinoma in Portugal. [PDF]

Front Vet Sci
Oliveira C, Santos J, Valença A, Catarino J, Ramilo D, Matias M, Alves M, Maia C, Faísca P, Henriques J, Pereira A.   +10 more
europepmc   +1 more source

Plant Virus Immunotherapy for HPV‐Associated Oropharyngeal Squamous Cell Carcinoma

Advanced NanoBiomed Research, EarlyView.
Cowpea mosaic virus (CPMV) nanoparticles are safe and potent cancer immunotherapy candidates with strong immunomodulatory activity. CPMV activates innate immunity, which in turn drives adaptive immune responses and promotes durable, systemic antitumor effects.
Jessica Fernanda Affonso de Oliveira, Patrick Opdensteinen, Andrea Simms, Seongwon Jung, Giuliana P. Mognol, Hui Chen, Judith A. Varner, Nicole F. Steinmetz   +7 more
wiley   +1 more source

Primary pancreatic squamous cell carcinoma with duodenal invasion: Literature review and a case report. [PDF]

Radiol Case Rep
Fatah FH, Hofmann A, Crane A, Seifi S, Veluvolu A, Wellman G, Shokouh-Amiri H, Zibari GB.   +7 more
europepmc   +1 more source

Are There CT Imaging Features That Can Distinguish Primary Pulmonary Squamous Cell Carcinoma from Solitary Lung Metastasis of Head and Neck Squamous Cell Carcinoma? [PDF]

Cancers (Basel)
Oliveira CV, Liu CC, Mayoral M, Pagano AM, Ortiz EJ, Chang J, Lobaugh S, Capanu M, Ginsberg MS, Plodkowski AJ.   +9 more
europepmc   +1 more source

Morphological and morphometric aspects of the equine aortic valve: New insights for comparative studies in mammals

The Anatomical Record, EarlyView.
Abstract New data on the equine aortic valve obtained using advanced techniques is especially important given the greater availability of animal models for translational research. Here we characterized the morphological and morphometric aspects of the equine aortic valve from 60 healthy hearts collected at equine abattoirs.
Vitor Pires Pereira, Victoria Brondani de Oliveira, Carlos Eduardo Seyfert, Luciano de Morais‐Pinto   +3 more
wiley   +1 more source