Results 161 to 170 of about 1,404,226 (404)

A proteogenomic portrait of lung squamous cell carcinoma

Cell, 2021
S. Satpathy, Karsten Krug, P. M. J. Beltran, Sara R. Savage, F. Petralia, Chandan Kumar-Sinha, Yongchao Dou, B. Reva, M. H. Kane, S. Avanessian, S. Vasaikar, A. Krek, Jonathan T. Lei, Eric J. Jaehnig, T. Omelchenko, Y. Geffen, Erik J. Bergstrom, Vasileios Stathias, K. E. Christianson, David I Heiman, M. Cieslik, Song Cao, Xiaoyu Song, Jiayi Ji, Wenke Liu, Kai Li, Bo Wen, Yize Li, Z. Gümüş, M. Selvan, R. Soundararajan, Tanvi H Visal, M. G. Raso, E. Parra, Özgün Babur, Pankaj Vats, Shankara K. Anand, Tobias Schraink, MacIntosh G. Cornwell, F. M. Rodrigues, Houxiang Zhu, Chia-Kuei Mo, Yuping Zhang, F. Leprevost, Chen Huang, A. Chinnaiyan, Matthew A. Wyczalkowski, G. Omenn, Chelsea J. Newton, Stephan Schurer, Kelly V. Ruggles, D. Fenyö, S. Jewell, M. Thiagarajan, M. Mesri, H. Rodriguez, Sendurai A Mani, N. Udeshi, G. Getz, J. Suh, Q. K. Li, G. Hostetter, P. Paik, S. Dhanasekaran, R. Govindan, Li Ding, A. Robles, K. Clauser, A. Nesvizhskii, Pei Wang, Steve Carr, Bing Zhang, D. Mani, Michael A. Gillette, Alex E. Green, Alfredo Molinolo, Alicia Francis, A. Paulovich, Andrii Karnuta, A. Colaprico, B. Hindenach, B. Pruetz, B. Kubisa, B. Druker, Carissa A. Huynh, C. A. Goldthwaite, Chet Birger, C. Kinsinger, Corbin D. Jones, D. Rohrer, Dana R. Valley, D. Chan, David W. Chesla, D. Hansel, E. Ponomareva, Elizabeth Duffy, E. Burks, E. Schadt, E. S. Fedorov, E. An, Fei Ding, G. Wilson, H. Batra, Hui Zhang, Jennifer E. Maas, J. Eschbacher, K. Ketchum, K. Rodland, K. Hoadley, Kei Suzuki, K. S. Um, L. Qi, L. Bernard, M. Wiznerowicz, M. Wojtyś, M. Domagalski, M. Ellis, Maureen A. Dyer, M. Borucki, M. Anurag, M. Birrer, Midie Xu, M. Krotevich, Nancy V. Roche, N. Edwards, Negin Vatanian, N. R. Mucci, Nicollette Maunganidze, N. Gabrovski, O. Potapova, O. Fadare, Pamela Grady, P. McGarvey, P. Hariharan, Ratna R. Thangudu, Rebecca Montgomery, R. Pandurengan, Richard D. Smith, R. Welsh, S. Mareedu, S. Payne, S. Cottingham, Shilpi Singh, S. Tsang, S. Cai, S. Gabriel, Tao Liu, Tara Hiltke, T. Vashist, Thomas Bauer, V. Sovenko, Warren G. Tourtellotte, Weiping Ma, William Bocik, Wohaib Hasan, Xiaojun Jing, Ximing Tang, Yuxing Liao, Yvonne, Shutack, Zhen Zhang, Ziad Hanhan   +161 more
semanticscholar   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

Squamous Cell Carcinoma

, 2012
In addition to urothelial carcinoma, adenocarcinoma, and small cell carcinoma, squamous cell carcinoma represents a major morphologic subtype of bladder cancer that harbors unique pathogenetic and molecular alterations. In the United States, squamous cell carcinoma affects less than 5 % of all bladder cancer patients, with primary risk factors that ...
Amr Fergany, Donna E. Hansel
openaire   +4 more sources

CCL5hi Macrophages Interact with CD8+ T Cells and Potentiate Responsiveness to PD‐1 Blockade Plus Chemotherapy in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study has characterized a functionally distinct macrophage subset, termed CCL5hi macrophages, and elucidated the underlying mechanisms of a regulatory feedback loop that interconnects IFN‐γ, CCL5hi macrophages, and CD8+ T cells within the TME of ESCC undergoing immunochemotherapy.
Yuanzhen Ma, Xiaodong Su, Tingting Zeng, Chunlian Zhou, Guozhen Yang, Zengfei Xia, Chufeng Zeng, Jiarong Zhan, Xin‐Yuan Guan, Xu Zhang, Yan Li   +10 more
wiley   +1 more source

Squamous Cell Carcinoma of the Lung and Squamous Cell Carcinoma of the Kidney [PDF]

Proceedings of the Royal Society of Medicine, 1961
L N Allen, D R Davies
openaire   +3 more sources

Epigenetic Activation of CCDC183‐AS1 Promotes Osteoclastogenesis and Prostate Cancer Bone Metastasis Through the FUBP1/LIGHT Axis

Advanced Science, EarlyView.
CCDC183‐AS1 overexpression enhanced the ability of PCa cells to spread to the bone by inducing osteoclastogenesis. Mechanistically, CCDC183‐AS1 interacted with FUBP1 and enhanced its stability, which promoted the transcription of TNFSF14 (LIGHT). Copy number gain‐induced KDM5C epigenetically upregulated CCDC183‐AS1 expression by recruiting TET1 to the ...
Chuandong Lang, Xiangyu Mu, Kun Chen, Xinwen Wang, Yuluo Rong, Jia Wang, Zongcheng Yang, Chi Yin, Yuhu Dai, Jun Xiao, Wenzhi Zhang   +10 more
wiley   +1 more source

Squamous-Celled Carcinoma of Left External Auditory Meatus [PDF]

, 1928
T. B. Jobson
openalex   +1 more source

Targeting Intratumoral Copper Inhibits Tumor Progression via p62‐Mediated EZH2 Degradation and Potentiates Anti‐PD‐1 Immunotherapy in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
The authors find that by targeting intratumoral copper, they can enhance p62‐mediated ubiquitination of EZH2 at the Ub‐K63 site by suppressing copper binding to SMURF2, an E3 ligase of EZH2, leading to its autophagic degradation. This mechanism suppressed OSCC progression and potentiated anti‐PD‐1 immunotherapy, highlighting a potential new therapeutic
Xiaohu Lin, Wanling Chen, Bo Li, Zhang Zhao, Zhonglin Yu, Xu‐Yun Zhao, Xuan Zhou, Zhien Feng, Chengzhong Lin, Wei Cao   +9 more
wiley   +1 more source

Histopathological Diagnostic Discordance between Punch Biopsies and Final Diagnostic Excisions of Cutaneous Squamous Cell Carcinoma: Analysis of 737 Cases

Acta Dermato-Venereologica
The recommended treatment for cutaneous squamous cell carcinoma is surgical excision. An initial punch biopsy is often performed as an aid to diagnosis.
Katherine Hopkins, Åsa Ingvar, Johan Palmgren, Valdis Thorhallsdottir, Kari Nielsen, Karim Saleh   +5 more
doaj   +1 more source

Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck.

New England Journal of Medicine, 2006
J. Bonner, P. Harari, J. Giralt, N. Azarnia, D. Shin, R. Cohen, Christopher U. Jones, R. Sur, D. Raben, J. Jassem, R. Ove, M. Kies, J. Baselga, H. Youssoufian, N. Amellal, E. Rowinsky, E. Rowinsky, K. Ang   +17 more
semanticscholar   +1 more source