Results 71 to 80 of about 2,184,154 (268)
Materia Arquitectura, 2014 The wave of urban protests characterized by the occupation of public space that has proliferated globally since 2010 has, as a common link, the questioning of representation models. Architecture, traditionally responsible for institutional representation
Urtzi Grau, Cristina Goberna
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FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Известия высших учебных заведений. Поволжский регион: Гуманитарные наукиBackground. The evolution of the urban landscape and the interaction of citizens with it is an integral part of the appearance of the city, which is reflected in the historical memory of the population.
A.A. Gushchin
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Наукові праці Лісівничої академії наук України, 2018 The aim of the paper is to assess the progressiveness and perfection of the modern functional classification of green spaces in settlements of Ukraine by comparing it with the one used earlier (in the 1950s) and the classifications currently used in ...
Vasyl Yukhnovskyi, Olga Zibtseva
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
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Shuffle squares and reverse shuffle squares
European Journal of Combinatorics16 ...
Xiaoyu He +3 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Translative Packing of Unit Squares into Squares
International Journal of Mathematics and Mathematical Sciences, 2012 Summary: Every collection of \(n\) (arbitrary-oriented) unit squares admits a translative packing into any square of side length \(\sqrt{2.5 \cdot n}\).
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source