Results 81 to 90 of about 2,184,154 (268)

Squaring the Square with Integer Linear Programming

open access: yesJournal of Information Processing, 2012
11 pages, 6 figures, 2 ...
openaire   +4 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Packing equal squares into a large square

open access: yesJournal of Combinatorial Theory, Series A, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Fan R. K. Chung, Ronald L. Graham
openaire   +3 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Inefficiency in packing squares with unit squares

open access: yesJournal of Combinatorial Theory, Series A, 1978
AbstractIt is shown that, in packing a square of side n + 12 with unit squares, the wasted space always has area ⪢ n12. This answers a question of Erdös and Graham.
K. F. Roth, Robert C. Vaughan
openaire   +2 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

PERGESERAN PERAN DAN FUNGSI ALUN-ALUN KALIWUNGU SEBAGAI RUANG TERBUKA PUBLIK

open access: yesJurnal Teknik Sipil dan Perencanaan, 2015
: The existence of the square Kaliwungu very far from the characteristics of such a square. Not only the shape, but the function of the square has also shifted away.
Lulut Indrianingrum   +3 more
doaj  

Los arrebatos del corazón Raptures of the Heart

open access: yesVaria História, 2006
En este artículo se exponen las peculiaridades historiograficas de los libros con fotografías en las que se ha abordado el devenir de la Plaza Mayor de la ciudad de México en el siglo XIX, se indica que en la mayoría de los casos se han considerado sólo ...
Fernando Aguayo Hernández
doaj   +1 more source

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