Results 101 to 110 of about 914,804 (316)
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
On the computation of the structured total least squares estimator
A class of structured total least squares problems is considered, in which the extended data matrix is partitioned into blocks and each of the blocks is (block) Toeplitz/Hankel structured, unstructured, or noise free.
Van Huffel, S. +2 more
core
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Local Regularization Assisted Orthogonal Least Squares Regression
A locally regularized orthogonal least squares (LROLS) algorithm is proposed for constructing parsimonious or sparse regression models that generalize well.
Chen, S.
core
Antarctic Ozone Enhancement During the 2019 Sudden Stratospheric Warming Event
We analyze the 2019 sudden stratospheric warming event that occurred in the Southern Hemisphere through its impact on the Antarctic ozone. Using temperature, ozone, and nitric acid data from the Infrared Atmospheric Sounding Interferometer (IASI), our ...
Sarah Safieddine +15 more
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The structured total least squares estimator, defined via a constrained optimization problem, is a generalization of the total least squares estimator when the data matrix and the applied correction satisfy given structural constraints.
Van Huffel, S. +2 more
core
A robust partial least squares method with applications [PDF]
Partial least squares regression (PLS) is a linear regression technique developed to relate many regressors to one or several response variables. Robust methods are introduced to reduce or remove the effect of outlying data points.
Romera, Rosario +2 more
core
Quasi-complete Latin squares: construction and randomization
A general method for constructing quasi-complete Latin squares based on groups is given. This method leads to a relatively straightforward way of counting the number of inequivalent quasi-complete Latin squares of side at most 9.
Bailey, Rosemary Anne +2 more
core +1 more source
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source

