Results 91 to 100 of about 914,804 (316)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Squaring the Square with Integer Linear Programming

Journal of Information Processing, 2012
11 pages, 6 figures, 2 ...
openaire   +3 more sources

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Total Least Squares Methods

, 2010
Recent advances in total least squares approaches for solving various errors-in-variables modeling problems are reviewed, with emphasis on the following generalizations: 1.
Markovsky, Ivan, Sima, Diana M., Van Huffel, Sabine   +2 more
core  

Shuffle squares and reverse shuffle squares

European Journal of Combinatorics
16 ...
Xiaoyu He, Emily Huang, Ihyun Nam, Rishubh Thaper   +3 more
openaire   +3 more sources

Packing equal squares into a large square

Journal of Combinatorial Theory, Series A, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Fan R. K. Chung, Ronald L. Graham
openaire   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Descriptive statistics of the partial least-squares-structural equation model (n = 78).

, 2023
Descriptive statistics of the partial least-squares-structural equation model (n = 78).
Naseem Al Rahhaleh (15810790), Abdullah Daghran Alahmari (15810796), Tawfeek A. Al-khyal (15810793), Mohammed Khaled Al-Hanawi (8379048)   +3 more
core   +1 more source

Insights into the spatial distribution of global, national, and subnational greenhouse gas emissions in the Emissions Database for Global Atmospheric Research (EDGAR v8.0) [PDF]

Earth System Science Data
To mitigate the impact of greenhouse gas (GHG) and air pollutant emissions, it is of utmost importance to understand where emissions occur. In the real world, atmospheric pollutants are produced by various human activities from point sources (e.g.
M. Crippa, D. Guizzardi, F. Pagani, M. Schiavina, M. Melchiorri, E. Pisoni, F. Graziosi, M. Muntean, J. Maes, L. Dijkstra, L. Dijkstra, M. Van Damme, M. Van Damme, L. Clarisse, P. Coheur   +14 more
doaj   +1 more source

Inefficiency in packing squares with unit squares

Journal of Combinatorial Theory, Series A, 1978
AbstractIt is shown that, in packing a square of side n + 12 with unit squares, the wasted space always has area ⪢ n12. This answers a question of Erdös and Graham.
K. F. Roth, Robert C. Vaughan
openaire   +2 more sources