Results 1 to 10 of about 72,541 (132)

Woolly Monkey–HBV Infection in Squirrel Monkeys as a Surrogate Nonhuman Primate Model of HBV Infection

Hepatology Communications, 2020
Development of curative therapies for chronic hepatitis B virus (HBV) infection will likely require new animal models. Here, we evaluate HBV infection in squirrel monkeys based on the high‐sequence homology of the HBV receptor, Na+/taurocholate co ...
Christopher Y. Chen, Benjamin Y. Winer, Deborah Chavez, Bernadette Guerra, Kathleen M. Brasky, Stacey Eng, Eduardo Salas, Danny Tam, Joe H. Simmons, Christian R. Abee, William E. Delaney, Alexander Ploss, Robert E. Lanford, Christian Voitenleitner   +13 more
doaj   +2 more sources

8-Substituted Triazolobenzodiazepines: In Vitro and In Vivo Pharmacology in Relation to Structural Docking at the α1 Subunit-Containing GABAA Receptor

Frontiers in Pharmacology, 2021
In order to develop improved anxiolytic drugs, 8-substituted analogs of triazolam were synthesized in an effort to discover compounds with selectivity for α2/α3 subunit-containing GABAA subtypes.
Lalit K. Golani, Donna M. Platt, Donna M. Platt, Daniela Rüedi-Bettschen, Daniela Rüedi-Bettschen, Chitra Edwanker, Shenming Huang, Michael M. Poe, Roman Furtmüller, Werner Sieghart, James M. Cook, James K. Rowlett, James K. Rowlett   +12 more
doaj   +1 more source

Emergence of Cryptosporidium hominis Monkey Genotype II and Novel Subtype Family Ik in the Squirrel Monkey (Saimiri sciureus) in China. [PDF]

PLoS ONE, 2015
A single Cryptosporidium isolate from a squirrel monkey with no clinical symptoms was obtained from a zoo in Ya'an city, China, and was genotyped by PCR amplification and DNA sequencing of the small-subunit ribosomal RNA (SSU rRNA), 70-kDa heat shock ...
Xuehan Liu, Na Xie, Wei Li, Ziyao Zhou, Zhijun Zhong, Liuhong Shen, Suizhong Cao, Xingming Yu, Yanchuan Hu, Weigang Chen, Gangneng Peng   +10 more
doaj   +1 more source

Photoacoustic imaging of squirrel monkey cortical and subcortical brain regions during peripheral electrical stimulation

Photoacoustics, 2022
The investigation of neuronal activity in non-human primate models is of critical importance due to their genetic similarity to human brains. In this study, we tested the feasibility of using photoacoustic imaging for the detection of cortical and ...
Kai-Wei Chang, Yunhao Zhu, Heather M. Hudson, Scott Barbay, David J. Guggenmos, Randolph J. Nudo, Xinmai Yang, Xueding Wang   +7 more
doaj   +1 more source

Prevalence and antimicrobial susceptibility of CTX‐M‐type‐producing Escherichia coli from a wildlife zoo in China

Veterinary Medicine and Science, 2022
Background Wildlife zoos provide the opportunity for children and adults to interact with animals, However, it's unknown that the risk of contact with animals, which carried zoonotic pathogens and antimicrobial resistant bacteria.
Ziyue Zeng, Jie Yang, Jinrong Gu, Zhihong Liu, Jufang Hu, Xiangyong Li, Xiaojun Chen, Zhiliang Sun, Jiyun Li   +8 more
doaj   +1 more source

Transthoracic echocardiography and cardiac biomarkers in healthy captive male and female squirrel monkeys (Saimiri spp.)

BMC Veterinary Research, 2020
Background Echocardiography is the most frequently used non -invasive diagnostic tool to evaluate cardiac anatomy and function in domestic species but increasingly also in non -domestic species, especially since cardiac disease is being recognized as an ...
Laurent Locquet, Blandine Houdellier, Bart J. G. Broeckx, Tim Bouts, Veronique Liekens, Jimmy H. Saunders, Pascale Smets   +6 more
doaj   +1 more source

Characterization of the Sweet Taste Receptor Tas1r2 from an Old World Monkey Species Rhesus Monkey and Species-Dependent Activation of the Monomeric Receptor by an Intense Sweetener Perillartine. [PDF]

PLoS ONE, 2016
Sweet state is a basic physiological sensation of humans and other mammals which is mediated by the broadly acting sweet taste receptor-the heterodimer of Tas1r2 (taste receptor type 1 member 2) and Tas1r3 (taste receptor type 1 member 3).
Chenggu Cai, Hua Jiang, Lei Li, Tianming Liu, Xuejie Song, Bo Liu   +5 more
doaj   +1 more source

Successful blastocyst production by intracytoplasmic injection of sperm after in vitro maturation of follicular oocytes obtained from immature female squirrel monkeys (Saimiri boliviensis)

The Journal of Reproduction and Development, 2021
Advanced reproductive technologies are being applied for the propagation of squirrel monkeys, to ensure their preservation as a genetic resource and the effective use of their gametes in the future.
Shinichi WATANABE, Megumi MIURA, Hiromi MORITA, Moeka NISHI, Shin-ichi YOKOTA, Shosaku HATTORI, Hiromichi MATSUMOTO, Emiko FUKUI, Ken Takeshi KUSAKABE, Masanori OCHI, Naomi NAKAGATA, Yasuo KISO, Chieko KAI, Midori YOSHIZAWA   +13 more
doaj   +1 more source

Identification of multiple TAR DNA binding protein retropseudogene lineages during the evolution of primates

Scientific Reports, 2022
The TAR DNA Binding Protein (TARDBP) gene has become relevant after the discovery of its several pathogenic mutations. The lack of evolutionary history is in contrast to the amount of studies found in the literature.
Juan C. Opazo, Kattina Zavala, Luis Vargas-Chacoff, Francisco J. Morera, Gonzalo A. Mardones   +4 more
doaj   +1 more source

Cholesterol metabolism in rhesus monkey, squirrel monkey, and baboon

Journal of Lipid Research, 1974
The metabolism of cholesterol wastudied in baboons, rhesus monkeys, and squirrel monkeys while they were being fed either a low fat, low cholesterol (basal) diet or the basal diet supplemented with saturated fat and cholesterol (atherogenic diet).
Douglas A. Eggen
doaj   +1 more source