Results 61 to 70 of about 3,555,062 (324)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Effect of Sr doping on structure, morphology and transport properties of Bi$_2$Se$_3$ epitaxial thin films

, 2019
We report molecular beam epitaxy growth of Sr-doped Bi$_2$Se$_3$ films on (111) BaF$_2$ substrate, aimed to realize unusual superconducting properties inherent to Sr$_x$Bi$_2$Se$_3$ single crystals.
Bryzgalov, M. A., Kuntsevich, A. Yu., Martovitskii, V. P., Selivanov, Yu. G., Volosheniuk, S. O.   +4 more
core   +1 more source

Sensitivity to reward and adolescents’ unhealthy snacking and drinking behavior: the role of hedonic eating styles and availability [PDF]

, 2016
Background: Although previous research found a positive association between sensitivity to reward (SR) and adolescents' unhealthy snacking and drinking behavior, mechanisms explaining these associations remain to be explored.
Beullens, Kathleen, Braet, Caroline, De Clercq, Bart, De Cock, Nathalie, Deforche, Benedicte, Eggermont, Steven, Goossens, Lien, Huybregts, Lieven, Kolsteren, Patrick, Lachat, Carl, Maes, Lea, Van Camp, John, Van Lippevelde, Wendy, Vangeel, Jolien, Vervoort, Leentje   +14 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

"Zero-Shot" Super-Resolution using Deep Internal Learning

, 2017
Deep Learning has led to a dramatic leap in Super-Resolution (SR) performance in the past few years. However, being supervised, these SR methods are restricted to specific training data, where the acquisition of the low-resolution (LR) images from their ...
Cohen, Nadav, Irani, Michal, Shocher, Assaf   +2 more
core   +1 more source

Enhancement of Tc by Sr substitution for Ba in Hg-2212 superconductor [PDF]

, 2003
The Ba substitution by Sr has been studied in two Hg-2212 series: Hg2(Ba(1-y)Sr(y))2YCu2O8-d and Hg2(Ba(1-y)Sr(y))2(Y0.80Ca0.20)Cu2O8-d. In both series a Tc enhancement of about 40 K is observed when Sr substitutes Ba from y = 0 to y = 1.0.
Odier, P., Toulemonde, P.
core   +3 more sources

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Electronic structure study of double perovskites $A_{2}$FeReO$_{6}$ (A=Ba,Sr,Ca) and Sr$_{2}M$MoO$_{6}$ (M=Cr,Mn,Fe,Co) by LSDA and LSDA+U

, 2001
We have implemented a systematic LSDA and LSDA+U study of the double perovskites $A_{2}$FeReO$_{6}$ (A=Ba,Sr,Ca) and Sr$_{2}$$M$MoO$_{6}$ (M=Cr,Mn,Fe,Co) for understanding of their intriguing electronic and magnetic properties.
A.E. Bocquet, A.J. Millis, C. Zener, D.D. Sarma, G.-m. Zhao, H. Wu, H. Wu, Hua Wu, J. Gopalakrishnan, K.-I. Kobayashi, K.-I. Kobayashi, M. Itoh, M.T. Anderson, P. Hohenberg, P.W. Anderson, Pan Wei, R.D. Shannon, R.S. Mulliken, U. von Barth, V.I. Anisimov, W. Kohn, W.E. Pickett, W.E. Pickett, Y. Moritomo, Y. Moritomo, Y. Tomioka, Z. Fang   +26 more
core   +1 more source

A Multi-Wavelength Analysis of Dust and Gas in the SR 24S Transition Disk [PDF]

, 2017
We present new Atacama Large Millimeter/sub-millimeter Array (ALMA) 1.3 mm continuum observations of the SR 24S transition disk with an angular resolution $\lesssim0.18"$ (12 au radius).
Andrews, S., Ataiee, S., Benisty, M., Birnstiel, T., Juhász, A., Natta, A., Pinilla, P., Pérez, L. M., Ricci, L., Testi, L., van der Marel, N., van Dishoeck, E. F.   +11 more
core   +5 more sources

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source