Results 41 to 50 of about 3,262,546 (268)

Strehl Ratio and Myopia in Chinese Adolescents: The Tuyou County Pediatric Eye (TYPE) Study

International Journal of General Medicine, 2021
Xiaoyan Bian,1,* Yuxia Guo,2,* Shixuan Guo,3,* Song Zhang,4,* Guisen Zhang,3 Lei Liu,4 Yajun Yang,5 Jun Liu6 1Department of Ocular Surface, Baotou Chaoju Eye Hospital, Baotou, 014060, People’s Republic of China; 2Department of Cataract Surgery ...
Bian X, Guo Y, Guo S, Zhang S, Zhang G, Liu L, Yang Y, Liu J   +7 more
doaj  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Changes in serum cholyglycine and prealbumin levels, glutamyl transpeptidase, and Alpha-fetoprotein after transcatheter arterial chemoembolisation combined with microwave ablation of liver cancer [PDF]

Journal of Medical Biochemistry
Background: This study aimed to evaluate the clinical outcomes of transcatheter arterial chemoembolisation (TACE) alone and in combination with microwave ablation (MWA) for patients with middle- or advanced-stage primary liver cancer (PLC) and analyse ...
Chen Kang, Zhang Chaojie, Sun Feihu, Sun Lei, Fan Chen, Wang Weidong   +5 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Chemical composition of modern and fossil hippopotamid teeth and implications for paleoenvironmental reconstructions and enamel formation : part 2, alkaline earth elements as tracers of watershed hydrochemistry and provenance [PDF]

, 2012
This study demonstrates that alkaline earth elements in enamel of hippopotamids, in particular Ba and Sr, are tracers for water provenance and hydrochemistry in terrestrial settings.
Brachert, Thomas C., Brügmann, Gerhard, Krause, Joachim, Kullmer, Ottmar, Mertz, Dieter F., Ssemmanda, Immaculate, Stoll, Brigitte, Weis, Ulrike   +7 more
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Development of a new measure to check attitude towards water conservation✰

MethodsX, 2023
Water Conservation is the need of the hour and attitudes towards conserving the resources is what is sure to become a priority in the coming years. In order to understand what could influence the change in attitude and thereby bring about a change of ...
R. Archana Reddy, Rakesh Sengupta, B. Micheal Jackson, Christelle Lewis   +3 more
doaj   +1 more source

⁸⁷Sr/⁸⁶Sr chemostratigraphy of Neoproterozoic Dalradian limestones of Scotland and Ireland: constraints on depositional ages and time scales [PDF]

, 2004
New calcite ⁸⁷Sr/⁸⁶Sr data for 47 limestones from the metamorphosed and deformed Neoproterozoic-Cambrian Dalradian Supergroup of Scotland and Ireland are used to identify secular trends in seawater <sup>
Ellam, R.M., Fallick, A.E., Graham, C.M., Thomas, C.W.   +3 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Spin Relaxation in a Quantized Hall Regime in Presence of a Disorder

, 2003
We study the spin relaxation (SR) of a two-dimensional electron gas (2DEG) in the quantized Hall regime and discuss the role of spatial inhomogeneity effects on the relaxation.
A. B. Dzyubenko, G. Bastard, I. V. Lerner, M. Dobers, M. I. D’yakonov, S. Dickmann, S. M. Dikman, S. M. Dikman, V. F. Gantmakher, V. Fock, Yu. A. Bychkov   +10 more
core   +1 more source