Results 61 to 70 of about 4,579 (195)

Abcc1 deficiency protects from corticosterone but not cortisol‐induced adiposity and insulin resistance in a sex‐specific manner

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A mouse model of exogenous glucocorticoid (GC) treatment was used to determine (1) if corticosterone induced the same metabolic dysregulation as cortisol, and (2) whether these differences were mediated by the corticosterone‐specific transmembrane exporter Abcc1.
Mhairi A. Paul   +9 more
wiley   +1 more source

Optimization of the A Constant for the SRK/T Formula

open access: yesOpen Journal of Ophthalmology, 2015
Purpose: To evaluate the effect of axial length (AL) and the average preoperative keratometry (K) on the A constant in the SRK/T formula. Methods: The retrospective, comparative case series includes 635 eyes from 407 cataract patients from Columbia University Medical Center from January 2006 to August 2010, operated by a single surgeon using a temporal
John C. Merriam   +3 more
openaire   +2 more sources

Accuracy of formulae for secondary intraocular lens power calculations in pediatric aphakia

open access: yesJournal of Current Ophthalmology, 2017
Purpose: To compare the accuracy of axial length vergence formulas versus refractive vergence formulas for secondary intraocular lens (IOL) implantation in pediatric aphakia. Methods: This retrospective comparative study, evaluated 31 eyes of 31 patients
Fouad R. Nakhli   +2 more
doaj   +1 more source

Steviol Glycosides (E960) From Stevia rebaudiana: Technological Innovations, Safety Assessment, Regulatory Aspects and Their Role in Sustainable Food Systems

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
Steviol Glycosides (E960) from Stevia rebaudiana: Technological Innovations, Safety Assessment, Regulatory Aspects and their Role in Sustainable Food Systems. ABSTRACT Stevia (Stevia rebaudiana Bertoni) is a small perennial herb widely recognized as a natural sweetener.
Aswin Sakthivel Manoharan   +1 more
wiley   +1 more source

Improving child mental health and learning outcomes and reducing stigma and discrimination in conflict setting: findings from a cluster randomized controlled trial of a classroom‐based psychosocial intervention in rural primary schools in Afghanistan

open access: yesJournal of Child Psychology and Psychiatry, Volume 67, Issue 7, Page 1127-1146, July 2026.
Background Conflict and crises have long‐lasting and dramatic consequences on the mental health of children. We aimed to investigate the effectiveness of a psychosocial intervention on child mental health in Afghanistan. Methods A two‐arm cluster‐randomized controlled trial was conducted in 83 rural primary schools within three provinces of Afghanistan.
Jean‐Francois Trani   +12 more
wiley   +1 more source

Activation of Self-Incompatibility Signaling in Transgenic Arabidopsis thaliana Is Independent of AP2-Based Clathrin-Mediated Endocytosis

open access: yesG3: Genes, Genomes, Genetics, 2018
Internalization of plasma membrane (PM)-localized ligand-activated receptor kinases and their trafficking to sorting endosomes have traditionally been viewed as functioning primarily in the down-regulation of receptor signaling, but are now considered to
Masaya Yamamoto   +2 more
doaj   +1 more source

Nemolizumab in prurigo nodularis up to 100 weeks: OLYMPIA LTE interim analysis

open access: yesJournal of the European Academy of Dermatology and Venereology, Volume 40, Issue 7, Page 1195-1207, July 2026.
In this interim analysis of the OLYMPIA long‐term extension trial, nemolizumab exhibited sustained efficacy and was well tolerated through 100 weeks, with most adverse events being mild/moderate. Patients showed clinically meaningful improvements in core signs and symptoms.
Franz J. Legat   +22 more
wiley   +1 more source

Comparison of OKULIX ray-tracing software with SRK-T and Hoffer-Q formula in intraocular lens power calculation

open access: yesJournal of Current Ophthalmology, 2018
Purpose: To compare the performance of OKULIX ray-tracing software with SRK-T and Hoffer Q formula in intraocular lens (IOL) power calculation in patients presenting with cataract.
Mohammad Ghoreyshi   +4 more
doaj   +1 more source

Affinity Enhancement in Discrete Multivalent MegaMolecules

open access: yesChemBioChem, Volume 27, Issue 11, 15 June 2026.
We design discrete protein megamolecules with precisely controlled valency (1–6 nanobodies), which exhibit strong avidity‐driven affinity enhancement toward epidermal growth factor receptor and human epidermal growth factor receptor. We systematically investigate the roles of valency, intrinsic affinity, and spatial presentation in optimizing binding ...
Zhaoyi Gu   +7 more
wiley   +1 more source

Comparison of SRK/T with Kane formula for prediction of refractive outcome after phacoemulsification: Insights from a South Asian patient group

open access: yesClinical Epidemiology and Global Health
Background: Phacoemulsification stands as the most commonly conducted ocular procedure. Biometry represents an art with numerous generations of formulas introduced to enhance refractive prediction accuracy. The Sanders Retzlaff Kraff theoretical (SRK/T),
Sana Nadeem
doaj   +1 more source

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