Results 11 to 20 of about 40,396 (302)
Mechanism for coordinate regulation of rpoS by sRNA-sRNA interaction in Escherichia coli [PDF]
RNA Biology, 2020 RpoS is a key regulator of general stress responses in Escherichia coli. Its expression is post-transcriptionally up-regulated by the small RNAs (sRNAs), ArcZ, DsrA and RprA, through sRNA-rpoS mRNA interactions. Although overexpression of the sRNA, CyaR,
Wonkyong Kim, Younghoon Lee
semanticscholar +3 more sources
Hfq CLASH uncovers sRNA-target interaction networks linked to nutrient availability adaptation
eLife, 2020 By shaping gene expression profiles, small RNAs (sRNAs) enable bacteria to efficiently adapt to changes in their environment. To better understand how Escherichia coli acclimatizes to nutrient availability, we performed UV cross-linking, ligation and ...
Ira Alexandra Iosub +8 more
doaj +2 more sources
Features of sRNA biogenesis in rice revealed by genetic dissection of sRNA expression level
Computational and Structural Biotechnology Journal, 2020 We previously conducted a QTL analysis of small RNA (sRNA) abundance in flag leaves of an immortalized rice F2 (IMF2) population by aligning sRNA reads to the reference genome to quantify the expression levels of sRNAs.
Wen Yao, Yang Li, Weibo Xie, Lei Wang
doaj +3 more sources
Modeling sRNA-regulated Plasmid Maintenance
PLOS ONE, 2016 We study a theoretical model for the toxin-antitoxin (hok/sok) mechanism for plasmid maintenance in bacteria. Toxin-antitoxin systems enforce the maintenance of a plasmid through post-segregational killing of cells that have lost the plasmid.
Gong, Chen Chris, Klumpp, Stefan
core +8 more sources
mBio, 2020 Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen causing skin and soft tissue, respiratory, and bloodstream infections. The type III secretion system (T3SS) is one important virulence factor.
Kayley H. Janssen +10 more
doaj +2 more sources
sRNA-controlled iron sparing response in Staphylococci [PDF]
bioRxiv, 2022 Staphylococcus aureus, a human opportunist pathogen, adjusts its metabolism to cope with iron deprivation within the host. We investigated the potential role of small non-coding RNAs (sRNAs) in dictating this process.
Rodrigo H. Coronel‐Tellez +8 more
openalex +2 more sources
Genome-wide identification of the context-dependent sRNA expression in Mycobacterium tuberculosis [PDF]
BMC Genomics, 2020 Tuberculosis remains one of the leading causes of morbidity and mortality worldwide. Therefore, understanding the pathophysiology of Mycobacterium tuberculosis is imperative for developing new drugs.
Vimla Kany G. Ami +2 more
openalex +2 more sources
NsrR1, a Nitrogen stress-repressed sRNA, contributes to the regulation of nblA in Nostoc sp. PCC 7120 [PDF]
Frontiers in Microbiology, 2018 Small regulatory RNAs (sRNAs) are currently considered as major post-transcriptional regulators of gene expression in bacteria. The interplay between sRNAs and transcription factors leads to complex regulatory networks in which both transcription factors
Muro Pastor, Alicia María +2 more
core +4 more sources
An Improved Description of the Small RNA Landscape of the Human Fungal Pathogen Aspergillus fumigatus. [PDF]
Mol MicrobiolThe mechanisms of small RNA biogenesis in fungi are diverse and multifactorial. Here, we provide an improved understanding of the processing of double‐stranded RNA in the human fungal pathogen Aspergillus fumigatus, revealing susceptibility to high levels of double‐stranded RNA and limited input of the canonical RNAi machinery on the endogenous small ...
Pan X +5 more
europepmc +2 more sources
Hfq-licensed RNA–RNA interactome in Pseudomonas aeruginosa reveals a keystone sRNA
Proceedings of the National Academy of Sciences of the United States of America, 2023 Significance Hfq is a key posttranscriptional regulator that modulates base-pairing interactions between sRNAs and their target mRNAs. Although there are more than 100 different sRNAs in Pseudomonas aeruginosa, information on their regulatory targets was
Michael J. Gebhardt +5 more
semanticscholar +1 more source