Results 171 to 180 of about 50,104 (262)

The Trouble with Trials: Systematic Review and Meta-Analysis of Randomized Controlled Trials Comparing Stereotactic Radiosurgery, Whole Brain Radiotherapy, and Observation for Resected Metastatic Brain Disease. [PDF]

Cancers (Basel)
St Brice K, Stevens B, Perry A, Lu VM, McClelland S, Gunter T, Graffeo CS.   +6 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Surgical Resection of Metastatic Male Breast Cancer to the Brain: An Illustrative Case Report. [PDF]

Clin Case Rep
Pio F, Fleisher MS, Obeidallah M, Mitchell M, Daggubati L.   +4 more
europepmc   +1 more source

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

Advanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li, Ka Man Ng, Xingsheng Shu, Xiaoxue Chai, Kai Yau Wong, Gopesh Srivastava, Anthony T.C. Chan, Wai Yee Chan, Qian Tao   +8 more
wiley   +1 more source

External Beam Radiation Therapy for Pheochromocytoma and Non-Head and Neck Paraganglioma: A Single-Institution Experience and Systematic Review. [PDF]

Cancers (Basel)
Jin KS, Wan M, Chau K, Nguyen C, Jackson S, Kollipara T, Whitaker E, Pollom EL.   +7 more
europepmc   +1 more source

Sustainable Fabrication of Tailored Bone Substitutes: From High‐Throughput Scaffold Manufacturing, Scaled‐Up HMSC Expansion to Dynamic Cultivation in a Perfusion Bioreactor

Advanced Science, EarlyView.
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun, Anna Paříková, Sandra Rother, Martin Kantor, Salman Muhammad Ilyas, Ricardo Bernhardt, Pavel Ndjawa Yomi, Jaromír Havlica, Revathi Appali, Benjamin Kruppke, Poh Soo Lee   +10 more
wiley   +1 more source

Patterns of failure following stereotactic radiosurgery salvage for recurrent high-grade glioma. [PDF]

J Neurooncol
Bindal S, Gonzalez B, Dono A, Riascos R, Zhu JJ, Hsu S, Tandon N, Blanco A, Esquenazi Y, Amsbaugh M.   +9 more
europepmc   +1 more source

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

Advanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu, Tianshuo Wei, Yan Ge, Bo Peng, Yue Li, Maolin Wang, Peng Wen, Chao Yang, Ye Wei   +8 more
wiley   +1 more source

Stimulated Raman Spectroscopy for Intraoperative Glioblastoma Diagnosis-A Complementary Tool to Frozen Section? [PDF]

Cancers (Basel)
Sippl C, Stark F, Schneider KI, Reyes Medina B, Schulz-Schaeffer W, Brinkmann M, Neumann F, Droop R, Ullmann S, Würthwein T, Hellwig T, Hoffmann L, Monfroy N, Khafaji F, Saffour S, Gaber K, Linsler S.   +16 more
europepmc   +1 more source