Gan to kagaku ryoho. Cancer & chemotherapy, 1986 The antitumor effect of a synthetic cord factor (6, 6'-Di-O-decanoyl-alpha, alpha-trehalose) (SS 554) on the growth of Meth-A fibrosarcoma in BALB/c mice was examined. With regard to administration routes, only intratumoral (i.t.) injection showed a curative effect; subcutaneous (s.c.), per oral (p.o.) or intravenous (i.v.) routes has no such effect ...
H, Kohya +5 more
openaire +3 more sources
Integration of SARS-CoV-2 RNA in infected human cells by retrotransposons: an unlikely hypothesis and old viral relationships [PDF]
, 2021 Zhang et al. (Proc Natl Acad Sci 118:e2105968118, 2021) recently reported that SARS-CoV-2 RNA can be retrotranscribed and integrated into the DNA of human cells by the L1 retrotransposon machinery.
Berkhout B., Grandi N., Tramontano E.
core +1 more source
Long-term glucocorticoid treatment and high relapse rate remain unresolved issues in the real-life management of polymyalgia rheumatica: a systematic literature review and meta-analysis [PDF]
, 2022 A systematic review and meta-analysis were conducted, according to the PRISMA methodology, to summarize current evidence on the prevalence and predictors of long-term glucocorticoid (GC) treatment and disease relapses in the real-life management of ...
Angioni, Maria Maddalena +7 more
core +4 more sources
Nutritional Status and Potentially Inappropriate Medications in Elderly: Real-World Experience [PDF]
, 2022 (1) Background: The association between polypharmacy and malnutrition has been investigated in several studies; however, few of these specifically deepened the relationship between potentially inappropriate medication and malnutrition. With a descriptive
Antonella Mandas +5 more
core +1 more source
Occupational exposure to ionizing radiation and risk of lymphoma subtypes: Results of the Epilymph European case-control study [PDF]
, 2020 Background: Evidence linking risk of lymphoma and B-cell lymphoma subtypes to ionizing radiation is inconclusive, particularly at low exposure levels.
Becker N. +14 more
core +7 more sources
The role of systemic statins in the inception and healing of apical periodontitis:A systematic review [PDF]
, 2023 Objectives:Statins are a category of medications widely used to reduce plasma LDL-cholesterol levels, that also possess antibacterial, anti-inflammatory, and immunomodulatory action.The aim of this systematic review was to explore the effects of systemic
Bardini, Giulia +5 more
core +3 more sources
RhVI1 is a membrane-anchored vacuolar invertase highly expressed in Rosa hybrida L. petals [PDF]
, 2016 Invertases are a widespread group of enzymes that catalyse the conversion of sucrose into fructose and glucose. Plants invertases and their substrates are essential factors that play an active role in primary metabolism and in cellular differentiation ...
Collu, Gabriella +4 more
core +1 more source
Takotsubo Syndrome is Associated with Mood Disorders and Antidepressants Use, not with Anxiety and Impairment of Quality of Life Due to the Psychiatric Disorder [PDF]
, 2018 Background: The aim was to study the association between mood and anxiety disorders and the Tako-Tsubo Syndrome (TTS) and to determine the role of antidepressants and the impairment of quality of life due the comorbid psychiatric disorder. Methods: Case-
Carta, Mauro G. +7 more
core +2 more sources
Working and Environmental Factors on Job Burnout: A Cross-sectional Study Among Nurses [PDF]
, 2016 Background: Burnout is a problem that impacts on the staff management costs and on the patient care quality. Objective: This work aimed to investigate some psychosocial factors related to burnout.
CAMPAGNA, MARCELLO +5 more
core +1 more source
Quality of life in carotid atherosclerosis: The role of co-morbid mood disorders [PDF]
, 2016 Introduction/Objective: To study in severe carotid atherosclerosis (CA): The frequency of mood disorders (MD); the impairment of quality of life (QoL); the role of co-morbid MD in such impairment. Methods: Case-control study.
CADONI, MICHELA +9 more
core +1 more source