Chemical Characterization and Anti-HIV-1 Activity Assessment of Iridoids and Flavonols from Scrophularia trifoliata [PDF]
Plants are the everlasting source of a wide spectrum of specialized metabolites, characterized by wide variability in term of chemical structures and different biological properties such antiviral activity.
Francesca Guzzo +9 more
doaj +2 more sources
Nanocrystalline TiO2 catalysts based on pure rutile (R100) and a 30% of anatase and 70% of rutile (R70) were synthesized by the sol-gel method, using Pluronic PE 6400 as templating agent.
Carmen Canevali +9 more
doaj +2 more sources
Comprehensive Analysis of HERV Transcriptome in HIV+ Cells: Absence of HML2 Activation and General Downregulation of Individual HERV Loci [PDF]
Human endogenous retrovirus (HERV) expression is currently studied for its possible activation by HIV infection. In this context, the HERV-K(HML2) group is the most investigated: it has been proposed that HIV-1 infection can prompt HML2 transcription ...
Nicole Grandi +4 more
doaj +2 more sources
Ultrasound Assessment in Polycystic Ovary Syndrome Diagnosis: From Origins to Future Perspectives—A Comprehensive Review [PDF]
Background: Polycystic ovary syndrome (PCOS) is the most prevalent endocrinopathy in women of reproductive age, characterized by a broad spectrum of clinical, metabolic, and ultrasound findings.
Stefano Di Michele +8 more
doaj +2 more sources
Occupational exposure to ionizing radiation and risk of lymphoma subtypes: results of the Epilymph European case-control study. [PDF]
Background: Evidence linking risk of lymphoma and B-cell lymphoma subtypes to ionizing radiation is inconclusive, particularly at low exposure levels.
Satta G +14 more
europepmc +9 more sources
Identification of HIV-1 Reverse Transcriptase-Associated Ribonuclease H Inhibitors Based on 2-Hydroxy-1,4-naphthoquinone Mannich Bases [PDF]
There is a strong demand for new and efficient antiviral compounds. A series of 2-hydroxy-1,4-naphthoquinone Mannich bases were screened for their HIV-1-RNase H inhibitory activity.
Nhat Quang Tu +9 more
doaj +2 more sources
New Thiazolidine-4-One Derivatives as SARS-CoV-2 Main Protease Inhibitors [PDF]
It has been more than four years since the first report of SARS-CoV-2, and humankind has experienced a pandemic with an unprecedented impact. Moreover, the new variants have made the situation even worse. Among viral enzymes, the SARS-CoV-2 main protease
Antonella Messore +22 more
doaj +2 more sources
Identification, comprehensive characterization, and comparative genomics of the HERV-K(HML8) integrations in the human genome. [PDF]
Around 8% of the human genome is composed by Human Endogenous Retroviruses (HERVs), ancient viral sequences inherited from the primate germ line after their infection by now extinct retroviruses.
Scognamiglio S +3 more
europepmc +3 more sources
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort [PDF]
Measurement(s) Cytopathic Effect Technology Type(s) confocal fluorescence microscopy Factor Type(s) Cellular toxicity Sample Characteristic - Organism Chlorocebus sabaeus Sample Characteristic - Environment continuant Sample Characteristic - Location ...
Andrea Zaliani +25 more
doaj +2 more sources
Photomechanochemistry: harnessing mechanical forces to enhance photochemical reactions [PDF]
Photomechanochemistry, i.e., the merger of light energy and mechanical forces, is emerging as a new trend in organic synthesis, enabling unique reactivities of fleeting excited states under solvent-minimized conditions.
Francesco Mele +6 more
doaj +2 more sources

