Results 131 to 140 of about 40,743 (286)

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman   +3 more
wiley   +1 more source

SSRI på internet : Vilka erfarenheter kring SSRI i samband med depression kommuniceras på nätet?

open access: yes, 2008
Depression är idag en folksjukdom i Sverige. Denna studie handlar om den allt större grupp deprimerade som behandlas med antidepressiva läkemedel. De mest använda preparaten i dag går under samlingsnamnet SSRI (Selektiva serotoninåterupptagshämmare ...
Arlert, Jonas
core   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux   +26 more
wiley   +1 more source

Technology Matters: Integrating digital treatments for children and young people with anxiety disorders into routine care

open access: yesChild and Adolescent Mental Health, EarlyView.
Anxiety disorders in children and young people are common and impairing. Cognitive behavioural therapy (CBT) is the recommended first‐line treatment and the past two decades have seen numerous digital CBT interventions emerge. Digital CBT has the potential to improve access, reduce waiting times and scale services.
Per Andrén   +2 more
wiley   +1 more source

The diagnostic order of migraine–depression comorbidity associates with physical, mental, and social disability

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background There is a known bidirectional association between migraine and depression; however, potential effects of the diagnostic trajectory of the diseases are not known. Therefore, we investigated the association of the diagnostic order of migraine and depression with the physical and mental health status of groups with ...
Daniel Baksa   +7 more
wiley   +1 more source

Swiss Practice Recommendations for Chronic Prurigo Including Prurigo Nodularis

open access: yesInternational Journal of Dermatology, EarlyView.
Chronic prurigo, including prurigo nodularis, is a chronic, often treatment‐refractory condition characterized by persistent pruritus and chronic scratch lesions. Advances in the understanding of its underlying pathophysiology have enabled the development of novel targeted therapies; however, management remains challenging due to the expanding range of
Simon M. Mueller   +11 more
wiley   +1 more source

Social cognition in children and adolescents with fragile X syndrome: A comparison with individuals with autism symptoms and typical development

open access: yesJournal of Neuropsychology, EarlyView.
Abstract Most individuals with fragile X syndrome (FXS) exhibit symptoms of autism spectrum disorder (ASD), suggesting a substantial overlap in social cognitive profiles. This cross‐sectional study aimed to explore social cognitive abilities in children and adolescents with FXS in comparison with an age‐matched heterogeneous ASD group and typically ...
Kamil R. Hiralal   +8 more
wiley   +1 more source

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