Results 41 to 50 of about 3,076,940 (300)

Association between clinical presentations before myocardial infarction and coronary mortality: a prospective population-based study using linked electronic records. [PDF]

, 2014
BACKGROUND: Ischaemia in different arterial territories before acute myocardial infarction (AMI) may influence post-AMI outcomes. No studies have evaluated prospectively collected information on ischaemia and its effect on short- and long-term coronary ...
Hemingway, Harry, Herrett, Emily, Smeeth, Liam, Bhaskaran, Krishnan, Denaxas, Spiros, Timmis, Adam   +5 more
core   +1 more source

Symptomatic Presentation of Acute Myocardial Infarction in Heart Transplantation Patients

JACC: Case Reports, 2021
Patients with acute myocardial infarction with a history of an orthotopic heart transplantation rarely present with classic anginal symptoms, secondary to cardiac denervation.
Shashank Jain, MD, Dexter D. Jacob, MD, Mahek K. Shah, MD, David L. Fischman, MD   +3 more
doaj   +1 more source

Bivalirudin started during emergency transport for primary PCI. [PDF]

, 2013
BACKGROUND: Bivalirudin, as compared with heparin and glycoprotein IIb/IIIa inhibitors, has been shown to reduce rates of bleeding and death in patients undergoing primary percutaneous coronary intervention (PCI).
Prats, Jayne, Grunsven, P. van, Zeymer, U., Pocock, Stuart, Campo dell' Orto, Marco, Huber, K., Clemmensen, Peter, Bernstein, D., Goldstein, Patrick, Coste, Pierre, Zeymer, Uwe, Clayton, T., Prats, J., Hamm, C.W., Orto, M. Campo dell', Clayton, Tim, Orto, Marco Campo Dell', Soulat, Louis, Deliargyris, E.N., Eggink, G.J., Hamon, Martial, et al., Bernstein, Debra, Eggink, Gerrit Jan, Steinmetz, Jacob, Nibbe, Lutz, Investigators, the EUROMAX, Berg, Jurrien Ten, Pocock, S., Mikkelsen, Søren; id_orcid, Steg, Philippe Gabriel, EUROMAX Investigators, Deliargyris, Efthymios N, Schuette, Diana, Berg, J. van den, Verheugt, F.W.A., Schuette, D., Soulat, L., Van Grunsven, Pierre, Nef, Holger, Coste, P., Huber, Kurt, Hamon, M., Hof, A. van't, Goldstein, P., Steinmetz, J., Lapostolle, F., Nibbe, L., Lapostolle, Frédéric, Nef, H., Hamm, Christian W, Steg, P.G., van 't Hof, Arnoud, Ten Berg, Jurrien, Clemmensen, P.   +54 more
core   +1 more source

Short-term and long-term outcomes in 133 429 emergency patients admitted with angina or myocardial infarction in Scotland, 1990-2000: population-based cohort study [PDF]

, 2006
Objective: To analyse short- and long-term outcomes and prognostic factors in a large population-based cohort of unselected patients with a first emergency admission for suspected acute coronary syndrome between 1990 and 2000 in Scotland. Methods: All
Frame, S., Boyd, J., Redpath, A., K MacIntyre, A Finlayson, A Redpath, S Capewell, J Boyd, Capewell, S., MacIntyre, K., Stewart, S., J W T Chalmers, Chalmers, J.W.T., N F Murphy, S Frame, S Stewart, Murphy, N.F., McMurray, J.J.V., J J V McMurray, Finlayson, A.   +19 more
core   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin, Dylan Hansen, Laura Ross, Gene‐Siew Ngian, Susanna Proudman, Gabor Major, Maryam Tabesh, Mandana Nikpour, Jennifer Walker, Lauren Host, Nava Ferdowsi, Alannah Quinlivan, Wendy Stevens, Joanne Sahhar, Diane Apostolopoulos   +14 more
wiley   +1 more source

Long-term effects of autologous bone marrow stem cell treatment in acute myocardial infarction: factors that may influence outcomes [PDF]

, 2012
AIMS: To investigate whether there are important sources of heterogeneity between the findings of different clinical trials which administer autologous stem cell treatment for acute myocardial infarction (AMI) and to evaluate what factors may influence ...
Anthony Mathur, Fisher Sheila A., Doree Carolyn, Doree, C, Mike J Clarke, Carolyn Doree (162145), Enca Martin-Rendon, Mathur Anthony, Clarke, MJ, Martin-Rendon Enca, Susan J Brunskill, Brunskill, Susan J., Susan J. Brunskill (162133), Watt, SM, Sheila A. Fisher (162124), Clifford, DM, Mike J. Clarke (162164), Watt Suzanne M., Carolyn Doree, Clifford, David M., Fisher, Sheila A., Brunskill, SJ, Suzanne M Watt, David M. Clifford (162115), Martin-Rendon, E, David M Clifford, Watt, Suzanne M., Brunskill Susan J., Clifford David M., Enca Martin-Rendon (162178), Suzanne M. Watt (162171), Fisher, SA, Doree, Caroyln, Mathur, Anthony, Clarke Mike J., Clarke, Michael, Anthony Mathur (162155), Sheila A Fisher, Martin-Rendon, Enca, Mathur, A   +39 more
core   +2 more sources

TAB2 Causes Neuronal Damage by Aggravating Microglia‐Mediated Neuroinflammation in Parkinson's Disease

Advanced Science, EarlyView.
In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao, Zimeng Huang, Jianing Gao, Aolan Li, Huizhi Wang, Yingchuan Chen, Guanyu Zhu, Xin Zhang, Yin Jiang, Moxuan Zhang, Fangang Meng, Jianguo Zhang, Tingting Du   +12 more
wiley   +1 more source

ST-Segment Elevation in the Right Precordial Leads in Patients with Acute Anterior Myocardial Infarction

Balkan Medical Journal, 2016
Background: Elevation of ST segment in leads V3R/V4R, which is commonly encountered in right ventricular myocardial infarction, may also occur in patients with anterior ST elevation myocardial infarction (STEMI).
Leili Pourafkari, Saeid Joudi, Samad Ghaffari, Arezou Tajlil, Babak Kazemi, Nader D. Nader   +5 more
doaj   +1 more source

Are There Options to Prevent Early Occurring Deaths in Acute Myocardial Infarction: Prospective Evaluation of All < 24 h In-Hospital Deaths, 2004-2006-The MONICA/KORA Augsburg Infarction Registry [PDF]

, 2010
Objectives: To provide valid clinical data of early in-hospital deaths with presumed acute myocardial infarction (AMI) who are often not included in clinical trials or registries.
Kuch, B., Kuch, Bernhard, von Scheidt, W., Anja Ehmann, Greschik, C., Ehmann, Anja, Birgitt Kling, Scheidt, Wolfgang von, Kling, Birgitt, Kling, B., Bernhard Kuch, Meisinger, Christa, Wolfgang von Scheidt, Claudia Greschik, Ehmann, A., Greschik, Claudia, Christa Meisinger, von Scheidt, Wolfgang, Meisinger, C.   +18 more
core   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source