Results 141 to 150 of about 37,398 (266)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

A randomized, observer-blind, phase 1 study of immune responses to three human adenovirus type 26 vector-based vaccines. [PDF]

EBioMedicine
Hertoghs N, Serroyen J, Tolboom J, van Heesbeen R, Ligtenberg N, Butler S, Merrall E, van Rosmalen M, Lavreys L, Maat-Ligthart M, McLean C, Luhn K, Hendriks J.   +12 more
europepmc   +1 more source

The stabilisation trick for coactions

When a locally compact group \(G\) is Abelian, a coaction \(\delta\) of \(G\) on a \(C^*\)-algebra \(A\) is given by an action \(\alpha\) of the dual group \(\widehat G\) on \(A\), and the crossed product \(A\times_\delta G\) by the coaction is isomorphic to the usual crossed product \(A\times_\alpha\widehat G\). A notion of twisted crossed products by
Echterhoff, S., Raeburn, I.
openaire   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Seed-mediated synthesis of NHC-stabilised Cu@Au core-shell nanoparticles from an NHC-Au(I) complex.

Nanoscale
Chalermnon M, Richstein R, Lichtenberger J, Grammatico D, Ge L, Wibowo RA, Chin JM, Reithofer MR.   +7 more
europepmc   +1 more source

Isolation and Reactivity of a Square-Planar Trisamido Silane. [PDF]

Angew Chem Int Ed Engl
Krengel DMJ, Wang X, Golz C, Herbst-Irmer R, Townrow OPE, Fischer M.   +5 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

<i>Ab initio</i> insights into hydrogen-rich polynuclear non-metallic superalkali cations. [PDF]

Front Chem
Srivastava AK.
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Why Luhmann? Social systems theory for a sociology of suicide in the platform age. [PDF]

Front Sociol
Fernández-Vilas E, Labora-González JJ, Coca JR.   +2 more
europepmc   +1 more source