Results 11 to 20 of about 835,285 (264)
Drug Analytical Research, 2023 Sitagliptin phosphate (STG), used for the treatment of type 2 diabetes, is a drug that belongs to a new class called inhibitors of dipeptidyl peptidase IV (DPPIV). It is known to be the first agent of the class approved by the FDA.
Alini Dall Cortivo Lange +3 more
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Stability-Indicating Chromatographic Methods for the Determination of Sertindole [PDF]
Journal of Chromatographic Science, 2013 In this work, two chromatographic methods have been developed and validated for the determination of sertindole (an antipsychotic agent) in the presence of its oxidative degradation product. Sertindole was subjected to stress stability studies, including acid, alkali, oxidative, photolytic and thermal degradation.
Nariman A, El-Ragehy +3 more
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Stability-indicating HPLC-DAD method for the determination of empagliflozin
Future Journal of Pharmaceutical Sciences, 2021 Background A stability-indicating RP-HPLC method was developed and validated for the estimation of empagliflozin drug and its tablet dosage form using a DAD detector. The mobile phase consisted of methanol/acetonitrile/0.1%OPA (75:20:5).
Shilpi Pathak, Pradeep Mishra
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Stability-indicating assay method for desonide in bulk and pharmaceutical formulation by HPTLC
Future Journal of Pharmaceutical Sciences, 2017 HPTLC method was developed for estimating the content of desonide in bulk and pharmaceutical formulation. Desonide is a topically applied low potency anti-inflammatory corticosteroid.
Pallavi P. Yeole +3 more
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Quantitative determination of imatinib stability under various stress conditions
Journal of Pharmacy and Bioallied Sciences, 2013 Objective: A simple, rapid, reverse phase and stability-indicating high-performance liquid chromatography (HPLC) method for the estimation of imatinib in solution and in plasma under forced degradation conditions was developed. Materials and Methods: The
Khalid Mohammed Alkharfy +4 more
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HPLC-UV METHOD APPROACH FOR THE ANALYSIS AND IMPURITY PROFILING OF CAPTOPRIL
Studia Universitatis Babes-Bolyai Chemia, 2019 The aim of the study was to propose an improved HPLC/UV method for captopril impurity profiling based on forced degradation studies. Material and methods: the HPLC-UV analyses were performed on a Luna C18 column at 50 0C by using a mobile phase ...
Anca Gabriela CÂRJE +6 more
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Future Journal of Pharmaceutical Sciences, 2021 Background Apigenin (4′, 5, 7-trihydroxyflavone), a flavonoid, is present usually in fruits and vegetables possessing numerous biological properties like antioxidant, anti-viral, antibacterial, anti-inflammatory, and chemoprevention activity.
Priya Shetti, Sunil S. Jalalpure
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Future Journal of Pharmaceutical Sciences, 2021 Background A novel gradient, high-sensitive and specific stability-indicating reverse-phase HPLC method was developed and validated for quantitative purpose of known, unknown and degradant impurities profiling for diltiazem hydrochloride tablets.
Nitin Mahajan +2 more
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Stability-Indicating Methods for the Determination of Disopyramide Phosphate [PDF]
Journal of AOAC INTERNATIONAL, 2006 Abstract Four methods were developed for the determination of intact disopyramide phosphate in the presence of its degradation product. In the first and second methods, third-derivative spectrophotometry and first derivative of the ratio spectra were used.
Maissa Y, Salem +3 more
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Drug Analytical Research, 2020 The purpose of this study was to develop and validate a fast HPLC stability-indicating method for simultaneously quantifying the four main isoflavones in Trifolium pratense. Validation procedures followed the ICH requirements for complex matrices.
Simony Martiny +4 more
doaj +7 more sources