Results 91 to 100 of about 8,363,118 (322)
THE STABILITY OF THE MINISUPERSPACE
Modern Physics Letters A, 1993 The stability of the minisuperspace model of the early universe is studied by solving the Wheeler-DeWitt equation numerically. We consider a system of Einstein gravity with a scalar field. When we solve the Wheeler-DeWitt equation, we pick up some inhomogeneous wave modes from infinite wave modes adequately: degrees of freedom of the superspace are ...
Ishikawa, Atushi, Isse, Toshiki
openaire +3 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Stability conditions on curves
, 2007 We study some examples of Bridgeland-Douglas stability conditions on triangulated categories. From one side we give a complete description of the stability manifolds for smooth projective curves of positive genus.
Macri, Emanuele
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The stability of modified gravity models
, 2005 Conditions for the existence and stability of de Sitter space in modified gravity are derived by considering inhomogeneous perturbations in a gauge-invariant formalism. The stability condition coincides with the corresponding condition for stability with
A. R. Liddle +11 more
core +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Does eductive stability imply evolutionary stability? [PDF]
This note presents a simple example of a model in which the unique rational expectations (RE) steady state equilibrium is eductively stable in the sense of Guesnerie (2002), but where evolutionary learning, as introduced in Brock and Hommes (1997), does ...
Hommes, C.H., Wagener, F.O.O.
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Quasistaticity of the process of dynamic strain of soils
Инженерно-строительный журнал, 2019 Mechanical characteristics of soil under static and dynamic strains are determined experimentally. Their accuracy and reliability depends on quasi-static nature of strain process in soil.
Karim Sultanov +3 more
doaj +1 more source