Results 11 to 20 of about 8,523,362 (276)
CRISPR-Associated Primase-Polymerases are implicated in prokaryotic CRISPR-Cas adaptation
Nature Communications, 2021 CAPPs are putative Primase-Polymerases associated with CRISPR-Cas operons. Here, the authors show CAPPs genetic and physical association with Cas1 and Cas2, their capacity to function as DNA-dependent DNA primases and DNA polymerases, and that Cas1-Cas2 ...
Katerina Zabrady +4 more
doaj +1 more source
eLife, 2021 The essential Smc5/6 complex is required in response to replication stress and is best known for ensuring the fidelity of homologous recombination. Using single-molecule tracking in live fission yeast to investigate Smc5/6 chromatin association, we show ...
Thomas J Etheridge +10 more
doaj +1 more source
Stability for Borell-Brascamp-Lieb inequalities [PDF]
, 2017 We study stability issues for the so-called Borell-Brascamp-Lieb inequalities, proving that when near equality is realized, the involved functions must be $L^1$-close to be $p$-concave and to coincide up to homotheties of their graphs.Comment: to appear ...
A. Dinghas +14 more
core +2 more sources
Inhibition of MRN activity by a telomere protein motif
Nature Communications, 2021 Telomeres suppress the DNA damage response at chromosome ends. Here the authors show that in budding yeast the activity of the MRX complex in DNA repair and DNA damage signaling is inhibited by telomeric protein Rif2 via a short motif at the N-terminus.
Freddy Khayat +11 more
doaj +1 more source
GIT semistability of Hilbert points of Milnor algebras [PDF]
, 2016 Our first result is that a homogeneous form $F$ in $n$ variables is GIT semistable with respect to the natural $SL(n)$-action if and only if the first non-trivial Hilbert point of the associated Milnor algebra is semistable.
Fedorchuk, Maksym
core +1 more source
Replication dynamics of recombination-dependent replication forks
Nature Communications, 2021 Replication forks that are stalled at obstacles on the DNA template can be restarted by homologous recombination. Here, the authors show replication dynamics during homologous recombination-dependent replication fork restart by combining polymerase usage
Karel Naiman +5 more
doaj +1 more source
The effect of a seismic wave on a two-span beam on rigid supports interacting with the ground [PDF]
E3S Web of Conferences, 2023 The transverse vibrations of a two-span beam bridge, the shore supports of which interact with the surrounding soil during seismic action, are considered.
Berdibaev Mars +3 more
doaj +1 more source
Nature Communications, 2018 Chromosome instability is associated with cancer formation. Here the authors identify in cultured human cancer cells a non-canonical DNA bridge breakage pathway leading to chromosome missegregation and rearrangements triggered by sister DNA ...
Ankana Tiwari +2 more
doaj +1 more source
A nucleotide resolution map of Top2-linked DNA breaks in the yeast and human genome
Nature Communications, 2019 Topoisomerase 2 (Top2) is known to resolve DNA topological stress through double strand breaks (DSBs), yet Top2 inhibition has been reported to result in a significant amount of single-strand breaks (SSBs).
William H. Gittens +5 more
doaj +1 more source
Stability of disk-like galaxies--Part I: Stability via reduction [PDF]
, 2006 We prove the existence and stability of flat steady states of the Vlasov-Poisson system, which in astrophysics are used as models of disk-like galaxies.
Firt, Roman, Rein, Gerhard
core +1 more source