Results 61 to 70 of about 8,363,118 (322)

Prophase-Specific Perinuclear Actin Coordinates Centrosome Separation and Positioning to Ensure Accurate Chromosome Segregation

Cell Reports, 2020
Summary: Centrosome separation in late G2/ early prophase requires precise spatial coordination that is determined by a balance of forces promoting and antagonizing separation. The major effector of centrosome separation is the kinesin Eg5.
Tom Stiff, Fabio R. Echegaray-Iturra, Harry J. Pink, Alex Herbert, Constantino Carlos Reyes-Aldasoro, Helfrid Hochegger   +5 more
doaj   +1 more source

The expanding amyloid family: Structure, stability, function, and pathogenesis [PDF]

, 2021
M.R. Sawaya, Michael P. Hughes, José A. Rodríguez, Roland Riek, David Eisenberg   +4 more
openalex   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

FEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji, Yuko Katayama, Nanase Arata, Mariko Sasaki   +3 more
wiley   +1 more source

Reorganization of Cell Compartmentalization Induced by Stress

Biomolecules, 2022
The discovery of intrinsically disordered proteins (IDPs) that do not have an ordered structure and nevertheless perform essential functions has opened a new era in the understanding of cellular compartmentalization.
Anna S. Fefilova, Iuliia A. Antifeeva, Anastasia A. Gavrilova, Konstantin K. Turoverov, Irina M. Kuznetsova, Alexander V. Fonin   +5 more
doaj   +1 more source

Interface engineering breaks both stability and activity limits of RuO2 for sustainable water oxidation [PDF]

, 2022
Kun Du, Lifu Zhang, Jieqiong Shan, Jiaxin Guo, Jing Mao, Chueh‐Cheng Yang, Chia‐Hsin Wang, Zhenpeng Hu, Tao Ling   +8 more
openalex   +1 more source

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

FEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji, Kosuke Shiraishi, Chuqian Wang, Hiroya Yurimoto, Yasuyoshi Sakai, Masahide Oku   +5 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Dynamical stability criterion for inhomogeneous quasi-stationary states in long-range systems

, 2010
We derive a necessary and sufficient condition of linear dynamical stability for inhomogeneous Vlasov stationary states of the Hamiltonian Mean Field (HMF) model.
Alessandro Campa, Antonov V A, Arnol’d V I, Arnol’d V I, Balescu R, Bartholomew P, Binney J, Campa A, Chavanis P H, Chavanis P H, Chavanis P H Campa A, Dauxois T, Ellis R, Elskens Y, Inagaki S, Konishi T, Lemou M Méhats F Raphael P, Lynden-Bell D, Nicholson D R, Pierre-Henri Chavanis, Tremaine S   +20 more
core   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source