Results 81 to 90 of about 10,939,833 (368)
Specialized interfaces of Smc5/6 control hinge stability and DNA association
Nature Communications, 2017 Structural Maintenance of Chromosomes (SMC) complexes maintain genome integrity by regulating the segregation of chromosomes. Here, Altet al. describe the structure of the heterodimeric Smc5/6-hinge from fission yeast and define functional features ...
Aaron Alt +10 more
doaj +1 more source
Cell Reports, 2020 Summary: Centrosome separation in late G2/ early prophase requires precise spatial coordination that is determined by a balance of forces promoting and antagonizing separation. The major effector of centrosome separation is the kinesin Eg5.
Tom Stiff +5 more
doaj +1 more source
High stability amplifier [PDF]
, 1983 An electrical RF signal amplifier for providing high temperature stability and RF isolation and comprised of an integrated circuit voltage regulator, a single transistor, and an integrated circuit operational amplifier mounted on a circuit board such ...
Adams, W. A., Reinhardt, V. S.
core +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Stability and stabilization of unstable condensates [PDF]
Physica Scripta, 2015 It is possible to condense a macroscopic number of bosons into a single mode. Adding interactions the question arises whether the condensate is stable. For repulsive interaction the answer is positive with regard to the ground-state, but what about a condensation in an excited mode?
openaire +4 more sources
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Strings, Junctions and Stability
, 2004 Identification of string junction states of pure SU(2) Seiberg-Witten theory as B-branes wrapped on a Calabi-Yau manifold in the geometric engineering limit is discussed.
A. Kumar +15 more
core +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
About J-flow, J-balanced metrics, uniform J-stability and K-stability
, 2017 From the work of Dervan-Keller, there exists a quantization of the critical equation for the J-flow. This leads to the notion of J-balanced metrics. We prove that the existence of J-balanced metrics has a purely algebro-geometric characterization in ...
Hashimoto, Yoshinori, Keller, Julien
core +3 more sources
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source