Results 81 to 90 of about 8,363,118 (322)

ATR Activates the S-M Checkpoint during Unperturbed Growth to Ensure Sufficient Replication Prior to Mitotic Onset

Cell Reports, 2013
Cells must accurately replicate and segregate their DNA once per cell cycle in order to successfully transmit genetic information. During S phase in the presence of agents that cause replication stress, ATR-dependent checkpoints regulate origin firing ...
John Kenneth Eykelenboom, Emma Christina Harte, Lynn Canavan, Ana Pastor-Peidro, Irene Calvo-Asensio, Marta Llorens-Agost, Noel Francis Lowndes   +6 more
doaj   +1 more source

Cdc14 phosphatase counteracts Cdk-dependent Dna2 phosphorylation to inhibit resection during recombinational DNA repair

Nature Communications, 2023
Cyclin-dependent kinase (Cdk) stimulates resection of DNA double-strand breaks ends to generate single-stranded DNA (ssDNA) needed for recombinational DNA repair.
Adrián Campos, Facundo Ramos, Lydia Iglesias, Celia Delgado, Eva Merino, Antonio Esperilla-Muñoz, Jaime Correa-Bordes, Andrés Clemente-Blanco   +7 more
doaj   +1 more source

Non-perturbative proton stability

, 2011
Proton decay is a generic prediction of GUT models and is therefore an important channel to detect the existence of unification or to set limits on GUT models.
Adam Martin, Gerben C. Stavenga, M. Nakahara, V. A. Kuzmin   +3 more
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

RETRACTED: Experiments on pressing elastic-viscous products [PDF]

BIO Web of Conferences
See the retraction notice BIO Web of Conferences 138, 00001 (2024), https://doi.org/10.1051/bioconf ...
Bahadirov Gayrat, Nabiev Ayder, Tsoy Gerasim   +2 more
doaj   +1 more source

Molecular basis for DNA repair synthesis on short gaps by mycobacterial Primase-Polymerase C

Nature Communications, 2020
Mycobacteria Prim-PolC performs short gap synthesis following removal of lesions during excision repair. Here the authors resolve crystal structures of pre- and post-catalytic Prim-PolC complexes bound to gapped DNA substrates to define its mechanism.
Nigel C. Brissett, Katerina Zabrady, Przemysław Płociński, Julie Bianchi, Małgorzata Korycka-Machała, Anna Brzostek, Jarosław Dziadek, Aidan J. Doherty   +7 more
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Study of resonant oscillations of an earth dam under seismic impacts considering dissipation in soil [PDF]

E3S Web of Conferences
The article proposes methods for numerically solving a nonstationary vibration problem of an earth dam using the finite element method in a plane formulation under dynamic impact.
Salyamova Klara, Nishonov Nematilla, An Ekaterina   +2 more
doaj   +1 more source

More Than One Step to Financial Stability [PDF]

Visiting Scholar Garry Schinasi examines the European proposals for the creation of both a European Systemic Risk Board (ESRB) to oversee macroprudential regulation and a European System of Financial Supervision (ESFS) to strengthen microprudential ...
Unknown
core   +1 more source

Application of three-body stability to globular clusters: I. The stability radius

, 2014
The tidal radius is commonly determined analytically by equating the tidal field of the galaxy to the gravitational potential of the cluster. Stars crossing this radius can move from orbiting the cluster centre to independently orbiting the galaxy.
Kennedy, Gareth F.
core   +1 more source