Results 181 to 190 of about 5,604,642 (305)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Long-Term Water Stability Analysis of Graphene-Composite-Modified Permeable Asphalt Mixture. [PDF]

Materials (Basel)
Ji S, Li Y, Wu X, Liang K, Cao X, Yuan X, Shen Q.   +6 more
europepmc   +1 more source

Structural Necessity of Questioning Systems A Control-Theoretic and Generative Analysis of Inquiry, Stability, and Collapse

YANG, JIHOON
openalex   +1 more source

Application of AVO Analysis to Seismic Data for Detection of Gas below Methane Hydrate Stability Zone in Nankai Trough Area [PDF]

, 2004
Masami Hato, Takao Inamori, Alfian Bahar, Toshifumi Matsuoka   +3 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

A yield design approach to the stability analysis of A seabed subjected to wave loading and pseudo-static seismic forces. [PDF]

Sci Rep
Quiuqui JPC, Maghous S.
europepmc   +1 more source

Determinants of Financial Stability in Nepalese Commercial Banks: An Empirical Analysis of Internal and External Factors

Shiva Raj Ghimire, Nirdosh Agarwal, Ashok Basnet   +2 more
openalex   +2 more sources

SLOPE STABILITY ANALYSIS USING THE SPRINGS ATTACHED TO THE INTERSLICE PLAINS

, 1997
Kanji Kondo, Setsuo HAYASHI
openalex   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Stability analysis of a tunnel face reinforced with bolts considering the intermediate principal stress component. [PDF]

Sci Rep
Xu K, Chen X, Luo G, Hu X, Li Y, Dai F, Chen J.   +6 more
europepmc   +1 more source