Results 221 to 230 of about 1,745,848 (340)

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Bielecki-Ulam stability of a hammerstein-type difference system. [PDF]

MethodsX
Rahmat G, Ahmad S, Sarwar M, Abodayeh K, Chasreechai S, Sitthiwirattham T.   +5 more
europepmc   +1 more source

Introduction to Control Theory. Part 3. State Space, Stability, and Lyapunov Functions

, 2015
Alexander Scheinker
openalex   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

Distributed sliding mode control approach with adaptive spacing policy for vehicle platoons in communication interruption scenario. [PDF]

Sci Rep
Wang J, Tong T, Cao J, Li S.
europepmc   +1 more source

Controlling and synchronizing a fractional-order chaotic system using stability theory of a time-varying fractional-order system

, 2018
Yu Huang, Dongfeng Wang, Jinying Zhang, Feng Guo   +3 more
openalex   +2 more sources

Optimized Cell‐Based Platform for Platelet‐Free Detection of Heparin‐Induced Thrombocytopenia Antibodies

Advanced Biology, EarlyView.
This study optimized a cell‐based ELISA for HIT antibody detection using PF4‐coated breast cancer cells (MDA‐MB‐231). Enhanced binding was observed at 50 mM NaCl and 4% paraformaldehyde fixation. Live MDA‐MB‐231 and HCT‐116 cells demontrated superior sensitivity and specificity, providing a promising platelet‐free alternative for clinical HIT diagnosis.
Li‐Yu Chen, Uwe Schirmer, Peter F. Zipfel, Doris Heinrich, Thi‐Huong Nguyen   +4 more
wiley   +1 more source

The double-edged sword effect of algorithmic management on work engagement of platform workers: the roles of appraisals and resources. [PDF]

Front Psychol
Li F, Zhan X, Liu Y.
europepmc   +1 more source

Modelling Atherosclerotic Plaque Cap Mechanics: Microcalcifications Reduce Mechanical Properties in Mesenchymal Stromal Cell‐Based Model

Advanced Biology, EarlyView.
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen, Deniz Şahin, Frank J.H. Gijsen, Eric Farrell, Kim van der Heiden   +4 more
wiley   +1 more source

Global dynamic characteristics of a piecewise smooth rotor/stator rubbing system with high speed. [PDF]

PLoS One
Wang S, Liu X, Liu Y, Ma J.
europepmc   +1 more source