Results 51 to 60 of about 2,852,150 (255)

An Accurate Method for Computing the Delay Margin in Load Frequency Control System with Gain and Phase Margins

Energies, 2022
In traditional power systems, a dedicated communication channel is utilized to transfer the frequency measurements. With the deregulation and reconstruction of power systems, the information is sent through a shared communication network that makes time ...
Ashraf Khalil, Dina Shona Laila
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Non-BPS walls of marginal stability [PDF]

Journal of High Energy Physics, 2013
Abstract We explore the properties of non-BPS multi-centre extremal black holes in ungauged $ \mathcal{N}=2 $ supergravity coupled to n v vector multiplets, as described by solutions to the composite non-BPS linear system.
Bossard, Guillaume, Katmadas, Stefanos
openaire   +4 more sources

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Calculation of the transient stability boundary of AC/DC inter‐connected system based on the stability margin of dynamic energy

IET Generation, Transmission & Distribution, 2022
Concerning the transient power angle stability problem in AC/DC inter‐connected system caused by DC line grounding fault, a transient stability analysis method based on the stability margin of dynamic energy is proposed. First, the analytical expressions
Jing Ma, Jiaming Zhang, Hongfei Shao, Peng Cheng   +3 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Stability Margin of Data-Driven LQR and Its Application to Consensus Problem

Mathematics
In contrast with traditional control input design techniques based on mathematical models of the system, in data-driven control approaches, which have recently gained substantial attention, the controller is derived directly from the data that are ...
Abdul Aris Umar, Kunhee Ryu, Juhoon Back, Jung-Su Kim   +3 more
doaj   +1 more source

Assigning the turning mode based on assessment of the dynamic quality of machine tools

Известия высших учебных заведений. Поволжский регион:Технические науки, 2023
Background. Machining on lathe machines using automation means is a complex process that depends on the properties of the dynamic system (DS) of the machine, therefore, determining cutting modes based on the minimum value of the attenuation coefficient
A.A. Ignat'ev, T.G. Nasad, V.A. Dobryakov, I.P. Nasad, A.A. Kazinskiy   +4 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Minimum Margin of stability.

, 2015
Example margin of stability data for one subject during a) a Known left trial and b) an Unknown left trial. Left (L) and Right (R) minimum margin of stability (MOS), denoted by “x” marker at each step, is the minimum distance between the base of support (
Jesse H. Matsubara (769254), Keith E. Gordon (769255), Mengnan Wu (769253)   +2 more
core   +1 more source