Results 181 to 190 of about 21,178 (307)

The spirit of the Constitution

, 2002
The article deals with the concept of the constitution which is analyzed on the basis of distinction between the normative and the descriptive methods.
Kūris, Egidijus
core  

Clinical characteristics of Mycoplasma pneumoniae pneumonia in children with atopic constitution and risk factors for disease severity: a retrospective comparative study. [PDF]

Front Pediatr
Liu Y, Fang Y, Chen P, Li W, Lu X.
europepmc   +1 more source

CONSTITUTIONAL REFORM: A THEORY OF STABILITY OR INSTABILITY OF THE DEMOCRATIC CONSTITUTIONAL PROJECT?

, 2015
This article aims to analyze to what extent the constitutional reforms imply stability or instability of the constitution. Under constitutionalism, the limitations imposed on the State are aimed at the maintenance and preservation of the democratic constitutional project built by political will manifested by the sovereign constituent assembly ...
openaire   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Study protocol for a randomized controlled trial to evaluate the effectiveness of an artificial intelligence-based health education accurately linking system based on traditional Chinese medicine body constitution in patients with chronic disease multimorbidity. [PDF]

Front Public Health
Liu Q, Yang Y, Hu Y, Yang X, Liu S, Bao R, Wu Y.   +6 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

The correlation between traditional Chinese medicine constitution and prediabetes: a systematic review and meta-analysis. [PDF]

Front Endocrinol (Lausanne)
Chen L, Wang Y, Xie X, Zhou Z, Xie L, Cai J, Li H, Zhang X, Ke Y, Li Q, Wu Z, Zhao X, Wang W.   +12 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Traditional Chinese medicine constitution and cardiometabolic multimorbidity: a nationwide cross-sectional study in older adults. [PDF]

Front Public Health
Chen R, Li HQ, Xia J, He FY, Zhang Y, Wang Z, Zhang HY, Yang YM, Bai MH, Ni C.   +9 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source