Results 41 to 50 of about 379,663 (282)

Integrity and Efficiency in the EU: The Case Against the European Economic Constitution. CES Working Paper, no. 130, 2006 [PDF]

open access: yes, 2006
The European Constitutional Treaty (ECT) was presented by its drafters as an explicit constitution for the European Union (EU 25). A possible explanation for its rejection by the French and Dutch citizens in the course of spring 2005 is that it did not ...
Laurent, Eloi,, Le Cacheux, Jacques.
core  

Constitution as a stabilizing factor of society development [PDF]

open access: yesActual Problems of Economics and Law, 2020
Objective: to study the Constitution as a stabilizing factor of social development.Methods: dialectical approach to the cognition of social phenomena that allows analyzing them in their historical development and functioning in the context of a set of objective and subjective factors, which determined the choice of the following research methods ...
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Choosing how to choose : self-stable majority rules and constitutions [PDF]

open access: yes, 2006
Constitutional arrangements affect the decisions made by a society. We study how this effect leads to preferences of citizens over constitutions; and ultimately how this has a feedback that determines which constitutions can survive in a given society ...
Barberà, Salvador,   +3 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Exploration of the High Entropy Alloy Space as a Constraint Satisfaction Problem [PDF]

open access: yes, 2017
High Entropy Alloys (HEAs), Multi-principal Component Alloys (MCA), or Compositionally Complex Alloys (CCAs) are alloys that contain multiple principal alloying elements. While many HEAs have been shown to have unique properties, their discovery has been
Abu-Odeh, Anas   +7 more
core   +1 more source

Constitutive Analyses of Nontraditional Stabilization Additives [PDF]

open access: yes, 2004
Abstract : Personnel of the U.S. Army Engineer Research and Development Center (ERDC), Vicksburg, MS, conducted a series of laboratory experiments designed to characterize the constitutive properties of selected soil minerals and nontraditional stabilization additives.
John F. Peters   +4 more
openaire   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Maintaining price stability: a proposal [PDF]

open access: yes
The Neal Resolution, now in Congress, would make price stability the dominant goal of monetary policy. The first of these two articles holds that policymakers’ discretion over the price level increases political conflict. Further, it argues that removing
Robert L. Hetzel
core  

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