Results 71 to 80 of about 379,663 (282)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Choosing How to Choose: Self-Stable Majority Rules and Constitutions [PDF]

open access: yes
Constitutional arrangements affect the decisions made by a society. We study how this effect leads to preferences of citizens over constitutions; and ultimately how this has a feedback that determines which constitutions can survive in a given society ...
Matthew O. JACKSON   +1 more
core  

Law as theory: constitutive thought in the formation of (legal) practice [PDF]

open access: yes, 2009
Law in its practical guise is found to have a constituent correspondence with ...
Fitzpatrick, Peter
core  

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Agenda for Change before the Republic of India [PDF]

open access: yes
Based on the electoral history of past 13 General Elections in the country, the paper argues that while the electorate has been pushing the political parties towards coalitions and grand alliances, the same are unlikely to be stable or effective.
Singh J P
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

How Theoretically Opposite Models of Interethnic Power-Sharing Can Complement Each Other and Contribute to Political Stabilization: The Case of Nigeria [PDF]

open access: yes, 2016
The aim of this article is to demonstrate the thesis that the stabilization of Nigeria’s complicated political situation is furthered by the functioning in that country of institutions based on two models of interethnic power-sharing – consociationalism ...
Trzcinski, Krzysztof
core  

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