Results 91 to 100 of about 55,201 (251)

Real‐World Effectiveness and Safety of Ravulizumab in Patients With Paroxysmal Nocturnal Hemoglobinuria: Evidence From the International PNH Registry

open access: yesAmerican Journal of Hematology, Volume 101, Issue 5, Page 939-948, May 2026.
ABSTRACT Ravulizumab, a second‐generation complement component 5 inhibitor (C5i) derived from eculizumab, with improved pharmacokinetics, is the current standard‐of‐care treatment for patients with paroxysmal nocturnal hemoglobinuria (PNH), where available.
Alexander Röth   +8 more
wiley   +1 more source

Effectiveness and Tolerability of Trimetazidine 80 mg Once Daily in Patients with Chronic Coronary Syndrome in Brazil: The V-GOOD Observational Study

open access: yesCardiology and Therapy
Introduction The V-GOOD study evaluated the effectiveness of trimetazidine modified-release (MR) 80 mg once daily (OD) in patients with chronic coronary syndrome (CCS) who remained symptomatic despite antianginal therapies in routine clinical practice ...
Luís Henrique Wolff Gowdak   +17 more
doaj   +1 more source

Batch Size Effects on Mid‐2025 State‐of‐the‐Art Large Language Model Performance in Automated Title and Abstract Screening

open access: yesCochrane Evidence Synthesis and Methods, Volume 4, Issue 3, May 2026.
ABSTRACT Background Manual abstract screening is a primary bottleneck in evidence synthesis. Emerging evidence suggests that large language models (LLMs) can automate this task, but their performance when processing multiple references simultaneously in “batches” is uncertain.
Petter Fagerberg   +6 more
wiley   +1 more source

CARDIOPROTECTION POTENTIAL IN CORONARY HEART DISEASE TREATMENT

open access: yesРоссийский кардиологический журнал, 2009
Aim. To investigate effectiveness and safety of trimetazidine MB in the complex treatment of stable angina. In total, 90 patients were examined – 57 women and 33 men aged 48-70 years (mean age 61,4 ± 6,03 years).
N. A. Shostak   +5 more
doaj  

Fungal Polysaccharides as Next‐Generation Bioactive: Advances in Structure–Activity Mapping, Mode of Action, and Biotechnological Horizons

open access: yesFood Frontiers, Volume 7, Issue 3, May 2026.
ABSTRACT Fungal polysaccharides (FPs) represent a diverse class of bioactive macromolecules widely studied for their nutritional, therapeutic, and biotechnological value. This review synthesizes recent advances (2020–2025) in the structural characterization, biological functions, and translational potential of FPs.
Muhammad Aaqil   +6 more
wiley   +1 more source

Cardiovascular Benefits of Salvia miltiorrhiza (Danshen) Supplementation: Bioactive Constituents, Mechanisms, Clinical Evidence and Implications for Nutritional Care

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
Salvia miltiorrhiza (Danshen) contains bioactive tanshinones, including tanshinone IIA, cryptotanshinone, and tanshinone I, that exert cardioprotective effects through coordinated modulation of vascular endothelial growth factor receptor (VEGFR), transforming growth factor beta 1 (TGF‐β1), transforming growth factor beta receptor (TGF‐βR), toll‐like ...
Akash Vikal   +6 more
wiley   +1 more source

Perindopril effects on circadian heart rate variability in patients with coronary heart disease and stable angina

open access: yesКардиоваскулярная терапия и профилактика, 2007
Aim. To study the effects of ACE inhibitor perindopril on circadian dynamic of heart rate variability (HRV) in patients with coronary heart disease (CHD) and stable effort angina. Material and methods.
N. A. Shardanov   +4 more
doaj  

Research and Scholarly Methods: Scoping Reviews

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 5, May 2026.
ABSTRACT Scoping reviews are similar to systematic reviews in that they are designed to be transparent and reproducible processes to answer a question while reducing bias. The key difference between scoping reviews and the better‐known systematic review method is the scope of the question being answered.
Jason B. Reed   +2 more
wiley   +1 more source

Utility of ranolazine in chronic stable angina patients

open access: yesVascular Health and Risk Management, 2008
Pawan D Patel, Rohit R AroraDepartment of Cardiology, Chicago Medical School, North Chicago, IL, USAAbstract: Chronic stable angina is a debilitating illness affecting at least 6.6 million US residents.
Pawan D Patel, Rohit R Arora
doaj  

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